Please login or register.

Login with username, password and session length
Advanced search  

News:

Menopause Matters magazine ISSUE 82 out now. (Winter issue, November 2025)

media

Author Topic: Prasterone as alternative to vagirux  (Read 1967 times)

FranJF

  • Member
  • *
  • Posts: 10
Prasterone as alternative to vagirux
« on: January 04, 2026, 04:05:53 PM »

Does anyone use Prasterone to control their vaginal atrophy instead of topical oestrogen?
I'm 66 and had VA diagnosed last August. I have vaginal soreness but my real problem symptom is the constant need to pee. I'm up 5 or 6 times each night and trying to have a normal life is impossible.
I use Vagirux internaly and estriol cream for the soreness but neither have improved the urinary frequency.
I've read that Prasterone ( DHEA) can be helpful for urinary problems so I'd be really interested on hearing your Personal experiences. Thanks.
Logged

CLKD

  • Member
  • *
  • Posts: 79402
  • changes can be scary, even when we want them
Re: Prasterone as alternative to vagirux
« Reply #1 on: January 04, 2026, 04:29:19 PM »

Important question: how often are U using the products and adding that many do not get on with Vagirux which is cheaper to dispense than Vagifem. 
Logged

FranJF

  • Member
  • *
  • Posts: 10
Re: Prasterone as alternative to vagirux
« Reply #2 on: January 04, 2026, 05:08:25 PM »

Hi CLKD,
I was using Estriol for 3 months, but only on the prescribed twice weekly dose after the initial loading period.
I'm now starting on my 2nd month of Vagirux which I'm taking daily. I expected to see some consistant improvement by now but I'm relatively ok(ish) one day and then back to being utter rubbish the following day.
I follow a very healthy diet, cutting out any potential triggers, don't smoke or drink and try to keep fit...not easy now as I need to stay near a toilet all the time. I'm desparate and miserable which seems to be a common theme with this horrible condition.
Logged

Minusminnie

  • Member
  • *
  • Posts: 755
Re: Prasterone as alternative to vagirux
« Reply #3 on: January 04, 2026, 06:03:52 PM »

As you are just starting your 2nd month you may need to give this more time & assess things after 3 or 4 months of use.

4 weeks use is likely not long enough but you do mention some days of improvement so that’s a start.
Logged

sheila99

  • Member
  • *
  • Posts: 6062
Re: Prasterone as alternative to vagirux
« Reply #4 on: January 04, 2026, 06:26:03 PM »

In the early days of my va testosterone stopped it but I had muscle weakness as well, presumably including weakness of the pelvic floor. If you don't I don't know if it will help but worth a try. Topical oestrogen twice a week didn't sort it out either. My GP wouldn't prescribe it more often so I have gone down the Newson route instead and use more systemic oestrogen than the NHS will allow me. Mine was continual leaking rather than urgency.
Logged

FranJF

  • Member
  • *
  • Posts: 10
Re: Prasterone as alternative to vagirux
« Reply #5 on: January 04, 2026, 06:37:45 PM »

As always, thank you for replies.
Sheila99, are your symptoms under control now and how long did it take for you be comfortable?
Logged

sheila99

  • Member
  • *
  • Posts: 6062
Re: Prasterone as alternative to vagirux
« Reply #6 on: January 04, 2026, 08:58:05 PM »

Yes, under control now but currently on 150 mcg oestrogen and tostran, no topical oestrogen. I can't remember accurately how long it took but I think about a month. Topical oestrogen didn't solve it for me but I was only allowed the daily loading dose for 2 weeks which wasn't enough, on 100mcg patch at the time. If your va is very bad sometimes the cream seems to absorb better than the pessaries.
Logged

FranJF

  • Member
  • *
  • Posts: 10
Re: Prasterone as alternative to vagirux
« Reply #7 on: January 04, 2026, 09:23:28 PM »

Glad to hear you have it under control, Sheila99.
I'm not on systemic hrt but I have another appointment at the end of this month so I'll discuss all my options then. Thank you
Logged

Arya Underfoot

  • Member
  • *
  • Posts: 43
Re: Prasterone as alternative to vagirux
« Reply #8 on: January 07, 2026, 01:33:25 AM »

I've been using Prasterone for about 3 months and have definitely had some improvements with my bladder, that was until my oestrogen levels dropped (I'm on the e implant). Before Prasterone I was using Vagifem 5 nights a week as well as Ovestin externally. Since you take it every night it really helps with dryness. I would recommend giving it a try but you may also have to try and increase your oestrogen levels to get some control over your bladder. I hope you find some relief soon, it really is horrible.
Logged

FranJF

  • Member
  • *
  • Posts: 10
Re: Prasterone as alternative to vagirux
« Reply #9 on: January 07, 2026, 09:53:46 AM »

Thank you Ayra underfoot
That is very useful information and something to discuss with the consultant.
Logged