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[Snowcat]

Is there anyone who can advise me on whether there are any alternatives in the UK to vaginal nystatin pessaries please?

I have .. azole resistant Candida Krusei which is driving me mad and no doctor seems to know what to prescribe .. the nystatin is no longer available and I don’t know what to do next … GP has given me
Econazole but when I looked it up it said that wouldn’t help at all …

Thank you :-)

[Nas]

Fluconazole?

[Snowcat]

Sorry Nas - I meant to say, it’s a fluconazole resistant strain which is why the 6 month course I had hasn’t worked …

[Nas]

Ah okay,  Damm, that’s a nuisance. Have the medics come
 up with any alternative for you?
Natural yoghurt? Tea tree oil?

[Snowcat]

Well that’s the strange thing - the lab report came up with nystatin pessaries but it’s impossible to get them.  They didn’t offer an alternative but my GP suggested Econazole but as far as I can find out it’s resistant to that one too - in fact any of the … azole family. 

[Nas]

I see. What is it, intense thrush, which won’t resolve? There HAS to be a remedy, surely. Have gynae any thoughts?

[Snowcat]

My urologist contacted a gynaecologist for me who also suggested the elusive nystatin pessaries … I’m going to go back to him tomorrow and ask for another suggestion - I’ll try to call my gynaecology dept on Tuesday when the one who’s been seeing me is in. If feels like normal thrush - burning and itching but is resistant to most known treatments.  But like you say there HAS to be something! I can’t be the only one in this situation!

[bombsh3ll]

Is it sensitive to griseofulvin and if so can you access this?

I would also make sure you have been tested for diabetes and that your vagina is well estrogenised.

[Donna-paul]

You can get Nystatin pessaries from Consultants at some hospitals. You can also order them online from a German pharmacy and they take a few days to arrive.

[Snowcat]

Thank you Bombsh311 - the only option they came up with was Nystatin so I’ve no idea what else it might be sensitive to unfortunately .. they were asked to do culture & sensitivities though.  I am diabetic but in remission as my blood sugars are within normal range - yay! I am using vagifem internally and estrogen cream as well as patches. 

[Snowcat]

You can get Nystatin pessaries from Consultants at some hospitals. You can also order them online from a German pharmacy and they take a few days to arrive.

Thank you so much Donna-Paul - I did wonder if it might be available at a hospital which is probably why my consultant says he has prescribed it in the past - he probably didn’t know it’s not used in primary care anymore.  I’ll ask him tomorrow if he can get some for me :-)

[dangermouse]

Nystatin Stada is the one you can get delivered from Europe.

There is also a Facebook group for Candida Krusai that may of help for you to join.

[Old Frumpy]

I believe there are certain medication that GP's can't precribe and only consultants and hospital pharmacies can.

Remember this from past treatment and having to contact consultants secretary when I required more.

So am sure tomorrow and seeing consultant will enlighten you.

Good  luck

[Snowcat]

Nystatin Stada is the one you can get delivered from Europe.

There is also a Facebook group for Candida Krusai that may of help for you to join.

Thank you Dangermouse - very helpful and I’ll have a look for that fb page :-)

[Snowcat]

I believe there are certain medication that GP's can't precribe and only consultants and hospital pharmacies can.

Remember this from past treatment and having to contact consultants secretary when I required more.

Thank you.  I’m now thinking this is the case.  The lab said Nystatin but My GP spoke to a specialist pharmacist who recommended Econazole but the read up on that for C.Krusei isn’t very promising but maybe I should give it a go - then he can’t blame me if I source something else.