Thankyou Mary for all that information.
Definitely progesterone is a necessity for your regime. Mine isn’t but, I do feel like it’s the missing piece for me. I’ve just had a trial and error process with so many meds this last few months and years that it’s a scary process.
I think you’re right that the Mirena stopped the effects of spiking and surging oestrogen with the first two (inserted 2018 and 2021) - oestrogen raises my histamine levels that set off my mast cells so calming the surge is esssential for me. So many of the symptoms I get are so like the symptoms people get for low oestrogen (hot flushes, anxiety, heart flutters, facial flushing, exhaustion, depression) but for me oestrogen is the devil. I tried oestrogel a few years ago before finding out all this and I felt poisoned.
So I’ve ordered the biovea but I would be really interested in what you all think would be best, to add progesterone cream to counter my E or to take stuff to minimise the impact of E a bit, like Dim and/or calcium d glucarate. My E levels have never ever been really high, even when not in peri my levels can range from 97 at the start of the cycle to 430 just before ovulation. But that’s enough E for me, in fact the day I tested 97 I felt really good as it was on day 3 of my cycle and the E hadn’t started rising loads yet.
I think Mary G and Dangermouse are knowledgeable on this. I think Dangermouse takes Dim. But obviously anyone who has an opinion please say!
Thanks ladies I really appreciate it xx