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[Scampidoodle]

Has anyone found any difference between the two? As in if you couldn’t tolerate utrogestan have you found cyclogest to be better? Unsure if they are that different.

I’ve tried utrogestan and my consultant suggested cyclogest so wondering if anyone had felt a difference?

[Mary G]

Scampi, I have had a box of Cyclogest knocking around for ages and because so many people are talking about it, I've decided to trial it - I am always happy to try something new.

I have a box of 400mg pessaries so I've cut one into 50mg doses and wrapped it in foil.  So far so good but obviously I don't want to tempt fate with my silent migraines. 

No noticeable side effects and no mess which many women report but that might be because of the low dose I'm using.  Definitely nowhere near as bad as Utrogestan. 

I still prefer the progesterone gel overall.

[Scampidoodle]

Hi Mary G! That’s good to know. I’m still not on any oestrogen yet (44) but managed to detox my oestrogen using sulphoraphane (broccoli and other things that assist oestrogen detox) and suddenly I have a 28 day cycle.

But my estrogen is a lot lower now. Like 271 at day 21. Ovulation was awful and pre period v tired and anxious but the rest of the time was good.

So in that difficult place in my cycles now where when my oestrogen is higher and detoxing I feel good and when it’s low I’m feeling it terribly

I produce no progesterone of my own now due to the Mirena coil.

Meno consultant suggested maybe using cyclogest. Either on its own or with a quarter patch of Estradot.

Was also thinking of cutting up the cyclogest to 50mg. Great you’re tolerating x

[Evie606]

Has anyone found any difference between the two? As in if you couldn’t tolerate utrogestan have you found cyclogest to be better? Unsure if they are that different.

I’ve tried utrogestan and my consultant suggested cyclogest so wondering if anyone had felt a difference?

Hi there,

I couldn’t tolerate Utro but am doing very well on Cyclogest for over 18 months now.
I use it rectally on a Conti regime 200mg on alternate nights.
The only very minor side effect is a bit of wind.

E x

[Scampidoodle]

Thanks Evie, what did utro cause for you?

Did you try cyclogest vaginally? And did that cause symptoms that made you swap to rectally? X

[Evie606]

Thanks Evie, what did utro cause for you?

Did you try cyclogest vaginally? And did that cause symptoms that made you swap to rectally? X

Utro made me feel like I was going mad, severe lows and anxiety.

Yes I tried it vaginally first but I have to say it was very messy and even with a panty liner, it wrecked many pairs of knickers. The residue is very waxy & sticky and nothing worked to wash it out.
Also, it made me quite bloated using it this way.
At least you have 2 options of delivery, hopefully one will work for you. X

[Scampidoodle]

Thankyou. I had a similar experience with utrogestan. It’s funny isn’t it as people say cyclogest and utrogestan are the same thing but people do tolerate them differently.

[Tribbins]

Utrogestan wasn't a good experience for me, so I tried Cyclogest which appeared to be ok to begin with. I had to stop after a month as the effect seemed to be cumulative. I just can't tolerate it. I was told at review it's Mirena or nothing as I would likely respond badly to other forms of progestogens. Currently I'm not using any but down to extremely low dose of Oestrogen (half a 25) and feeling better than I did (apart from returning migraines) - can't get any appointment with either GP or menopause-trained nurses so having to slowly stop using oestrogen. I really hope you can tolerate Cyclogest as there's a real lack of choice if you have sensitivity to progesterone.

[Furyan]

This summer, I swapped Utrogestan for Cyclogest as Cyclogest offers better flexibility for me. Whether I like it or not, I can’t take 100 or 200mg progesterone EVERY DAY. I need to take a little bit less than that so I cut my Cyclogest to anywehere between 50 and 70mg doses. You can’t cut Utrogestan. I also found that alternate day vaginal dosing of Utrogestan doesn’t suit me because of the discharge it produces and its potential interference (for me) with sexual intimacy. Cyclogest can be taken rectally so it gets rid of this. Just a pity that my GP practice refuse to prescribe it 

[Mary G]

Furyan, that is very interesting.  With progesterone, it's all about dose in my experience and if you get it wrong and take too much it's lethal.  One of the many problems with Utrogestan is its lack of flexibility.  I tried taking it every other day but it triggered my silent migraines. 

I'm now trialling Cyclogest @50mg but not every day.  I'm interspersing it between my progesterone gel because I've decided to try a mix and match approach.  Dose accuracy is not great because the wax pessary crumbles slightly but it's as near to 50mg as possible.  So far so good with zero side effects but not as calming as the progesterone gel.  I'm due a scan soon so it will be interesting to see if the womb lining is below the 5mm danger level.

Tribbins, what dose of Cyclogest were you taking?  Sorry to hear your migraines have returned but that will be because of the drop in oestrogen which in turn reduces seratonin levels - I have the same sub type of migraine.  If you have problems with progesterone, it would be better to go for the lower dose Myleena or Jaydess coil.  A Mirena might be too high a dose for you.

Scampi, I hope this is helping.

[Scampidoodle]

Thanks all. Appt next week so I’ll see what she says re cyclogest x

[Furyan]

Furyan, that is very interesting.  With progesterone, it's all about dose in my experience and if you get it wrong and take too much it's lethal.  One of the many problems with Utrogestan is its lack of flexibility.  I tried taking it every other day but it triggered my silent migraines. 

I'm now trialling Cyclogest @50mg but not every day.  I'm interspersing it between my progesterone gel because I've decided to try a mix and match approach.  Dose accuracy is not great because the wax pessary crumbles slightly but it's as near to 50mg as possible.  So far so good with zero side effects but not as calming as the progesterone gel.  I'm due a scan soon so it will be interesting to see if the womb lining is below the 5mm danger level.

Tribbins, what dose of Cyclogest were you taking?  Sorry to hear your migraines have returned but that will be because of the drop in oestrogen which in turn reduces seratonin levels - I have the same sub type of migraine.  If you have problems with progesterone, it would be better to go for the lower dose Myleena or Jaydess coil.  A Mirena might be too high a dose for you.

Scampi, I hope this is helping.

Mary - you’re right about progesterone dosing and some of us show more sensitivity to levels than the majority could perhaps get away with. On my oesteogen dose (equivalent to about 2 1/3 pumps of oestrogel) I can get away with 70mg of progesterone before it starts to affect my mood, fluid and tiredness. I have enough going on with my thyroid atm, so I can’t afford to go over and add to/confuse my symptoms. Interesting what you say about Cyclogest and mood as opposed to Utrogestan. I find it slightly more calming too, yet they are both micronised.

[Scampidoodle]

Hi all just to update I’m now on half a 25mcg Estradot patch. So far so good my mood is improved. I have histamine and mast cell issues so I can’t take a high dose.

I have the Mirena coil so don’t need progesterone but I may need to have it to calm the histamine as on the patch even at this small dose I have felt a real increase in symptoms.

Tried utrogestan again vaginally after I’d been on the patch and it did help the histamine to an extent but awful depression which seemed to build
Each day and I only managed 4 days!

So next step would be cyclogest cut up. Consultant says to cut a 100mg capsule  into thirds.

How are you getting on with it now Mary G?

[Gnatty]

Is the progesterone gel still available to buy? I'm having trouble sourcing it.

[joziel]

scampi one other thing you could try if the half a 25 patch idea doesn't work, is just using the patch for the first and last week of your cycle - when your own estrogen is lowest.