It's confusing, isn't it?
They claim to be bioidentical so you'd think they'd be similar doses, but from reading the bottle/packs the Evorel says it contains 3.2mg Estradiol of which it releases 50mcg Estradiol into the bloodstream, every day for four days, so that is a total delivery of 200mcg in four days, aka 0.2mg, the other 3mg degrades or goes in the bin.
That is supposed to be the same as two pumps of Oestrogel. Oestrogel says it contains 750mcg Estradiol per pump, so by smothering my arms in two pumps of that, I'm applying 2x750mcg=1.5mg Estradiol, that is thirty times the intended dose of 50mcg Estradiol.
I don't know what happens to the 1.45mg that doesn't end up in the bloodstream, but that is what they are saying, they estimate only one thirtieth of the applied gel, 50mcg, will end up in my bloodstream.
Now what happens if my skin is a little thicker or thinner than the skin they tested it on?
btw 1,000,000mcg=1,000mg=1g
My experience was that patches were useless. I went from a 50 patch to one pump of gel and I thought it was many times stronger, that one pump, it was supposed to be weaker. Now I'm on three pumps!