I don't know if this helps, but I have needed to increase my estradot several times, and I do so quite slowly.
I needed to go to 100,but I knowwhen I do increase I get a bit jittery, and breathless. So rather that jump straight to the 100, for a few doses, I cut a tiny sliver off, so I kind of went from 75 to 85 approx, so as to give my body time to adjust to a newer higher dose.
Today I have gone for the whole 100,and fingers crossed after a couple of days my body will lose the jitters and accept the higher dose.
Maybe this would help you if you did need to up your own dose?
Wishing you well