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Author Topic: Mirena progesterone in uterus only ?  (Read 7077 times)

Nas

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Re: Mirena progesterone in uterus only ?
« Reply #30 on: June 19, 2022, 11:27:15 AM »

Do you get depression on all progesterone Flossie? Utrogestan was great for my mood but didn’t control bleeding.

Now feel in between a rock and a hard place.

 X
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Flossieteacake

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Re: Mirena progesterone in uterus only ?
« Reply #31 on: June 19, 2022, 11:38:17 AM »

Do you get depression on all progesterone Flossie? Utrogestan was great for my mood but didn’t control bleeding.

Now feel in between a rock and a hard place.

 X

Yes I do. Is it possible for you to take a contraception pill to stop the bleeding? I know some people cannot. If it were me, I would prefer bleeding to the depression. I know we are all different though.
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joziel

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Re: Mirena progesterone in uterus only ?
« Reply #32 on: June 19, 2022, 12:22:13 PM »

Nas, it is known that the coil releases more progesterone in the first few months than it will do later.

So, even if you are having some systemic side effects, these should improve when the dose reduces. I wouldn't confuse things by changing other stuff (increasing estrogen) or you won't know what is causing what. Everyone always wants to Change Something, Do Something, when they experience side effects. Sitting with it and waiting and doing nothing is often the hardest thing, but the body is on biological time and things take their own sweet time...
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Nas

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Re: Mirena progesterone in uterus only ?
« Reply #33 on: June 19, 2022, 02:53:22 PM »

Yes joziel, you are absolutely right re: not changing anything just yet.

The trouble is, when you must work, interact with people, run a home, deal with teens etc etc,  having permanent PMS is not conducive with life.

It’s very tough.

I didn’t know the coil releases more progesterone in the first few months though.

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Marchlove

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Re: Mirena progesterone in uterus only ?
« Reply #34 on: June 19, 2022, 03:57:37 PM »

Oh yes indeed it does Nas, that’s why it takes a few months for things to settle down and so many women give up on it.

Do your family all know you have these PMS symptoms including the teens? X
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Nas

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Re: Mirena progesterone in uterus only ?
« Reply #35 on: June 19, 2022, 04:38:48 PM »

I warned my partner March and he’s trying to be patient with me.
The teens are just putting up it.

 Work is tricky. I work with SEN kids and was very snappy last week!

It really isn’t practical with everyday life to be this way. If it was weeks rather than months, I may think differently. But this PMS  is brutal!
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sheila99

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Re: Mirena progesterone in uterus only ?
« Reply #36 on: June 19, 2022, 05:52:57 PM »

If it doesn't settle you might consider a Jaydess instead, 14mcg vs 20 for the mirena. It doesn'tllast as long and I have no idea if you'd get it on the nhs.
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Marchlove

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Re: Mirena progesterone in uterus only ?
« Reply #37 on: June 19, 2022, 06:23:48 PM »

Try shouting Nas, really really loudly. Good when you’re in the car alone!
I used to shout ‘f…off’ over and over, also bashing a cushion about on the floor helps. Really go for it like a tigress! X
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Nas

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Re: Mirena progesterone in uterus only ?
« Reply #38 on: June 19, 2022, 06:38:39 PM »

March, you did make me chuckle!

Yes, will try that. Unfortunately it will be partner or son who gets the bashing, if I see any more mess in the house! 😬😀

Will see what this week brings. All these symptoms as far as I’ve read, appear ‘ normal’ but tough to endure when you’ve already had 3.5 years of being held hostage to hormones!
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Nicknak47

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Re: Mirena progesterone in uterus only ?
« Reply #39 on: June 19, 2022, 07:19:46 PM »

I spotted fir nearly 6 months but after heavy painful periods lasting a week it’s worth it cos after those first 6 months of spotting I had 2 very light pain free bleeds barely anything! So I’d get another one fitted when this one runs out for that reason . Just need to get my oestrogen levels up . I think you could do with 100 patch now instead .
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Nicknak47

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Re: Mirena progesterone in uterus only ?
« Reply #40 on: June 19, 2022, 07:39:15 PM »

If you can preserve with it it will be worth it for the reduction in bleeding and as part of the HRT to protect your womb alongside your patch but a higher one things will start to balance out for you . I work withSEN kids too and it’s stressful aswell as having teenagers so getting rid of periods is a blessing for me now just have joint pains now instead lol 😂
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Floradora

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Re: Mirena progesterone in uterus only ?
« Reply #41 on: June 20, 2022, 11:10:22 AM »

Oh I’m sorry to hear Mirena is causing you problems Nas. I thought it might be your answer. As others have said I suppose you have to give it a bit longer to see if things settle down. The crampy pms symptoms certainly do sound progestogen related. I think you are doing it in the right way trialling one thing over a period of time. It sounds as though for you, if you don’t get on with the Mirena, it will be a trade off between manageable symptom control but keeping your estrogen low enough that you don’t bleed on say Utrogesten ( which I think was one that you got on with ). The bleeding must be debilitating and it may be that you can very slowly reduce your estrogen dose over time until you find the ‘no bleed’ sweet spot. Hopefully the Mirena will settle in time and you maybe won’t have to try this x
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joziel

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Re: Mirena progesterone in uterus only ?
« Reply #42 on: June 20, 2022, 01:04:32 PM »

Yes, it does release more progesterone at first - I've searched to try to find where I read that. I can't find it, but it was official and not just someone's account or experience.

Newson Health pdf says: https://www.newsonhealth.co.uk/uploads/2021/07/Progesterone-Intolerance-v21-02.pdf

"Some women do react to the progestogen in the Mirena; when it’s first inserted it can feel like you have PMS for the first few months. Any reaction tends to settle down at around 3 to 6 months and most women do not continue to have symptoms of intolerance after this."
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Blue Kingfisher

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Re: Mirena progesterone in uterus only ?
« Reply #43 on: June 20, 2022, 01:15:49 PM »

Nas, just to say I’m so sorry you are having such a hard time. It’s like a never ending nightmare sometimes. I tried the Kyleena coil and had mine removed after a couple of months as I couldn’t stand it but to be honest I don’t feel much better now so could have misread my symptoms! All you want is for someone to tell you what will make you feel better but annoyingly we have to help ourselves when we are feeling totally rubbish. Thank goodness for this forum. Just take every day as it comes and see how you go. Big hug x
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sas67

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Re: Mirena progesterone in uterus only ?
« Reply #44 on: June 20, 2022, 01:34:12 PM »

Hello there
I have been longing to contribute to this thread, but the admins have only just approved me.  I had the Mirena fitted on 16th May, a couple of weeks before you Nas, and I am having it removed on Wednesday! 
I have a history of terrible PMS prior to having my children, so the Mirena was recommended as the gold standard for me.  My main perimenopausal symptoms have been depression and anxiety which were solved by being on a 100mcg evorel patch and doing two weeks of vaginal Utrogestan.  As the Mirena was supposed to be the most convenient way of keeping the womb lining thin and has very 'low systemic effects' I booked myself in for a fitting.  Literally the next day I was completely flat and the day after I cried all day which I don't think I have ever done before.  Then I continued to feel very flat, depressed, tearful, occasionally OK and intermittent  terrible brain lethargy.  I saw a private menopause specialist and she said stick with it for three months, but after reading all the stories on mums net and elsewhere on the internet I decided that I'm not going to risk it never getting better.  I also thought that the progesterone component was a body identical progesterone like Utrogestan but actually it's the same synthetic progestin that is in the pill I took in my twenties which took away my libido and probably contributed to depression and pms.  Clearly the Mirena works brilliantly for most people but the psychiatric side effects are well known and listed on the leaflet that comes with it and if you've had a history of pms then you are more likely to be one of the unlucky ones who finds it a struggle.  I will let you know if I notice any changes when I have it removed.
Thanks for reading and good luck to you!
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