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[CrispyChick]

Morning gill

Yes. That's kind of what I was getting at. I do t wa t to sound like a peri book, but as we move towards meno we'll prob start having more annovulatory cycles.

For me, my first ever blood test was recorded on an annovulatory month (I know because I get intense ovulation pain). My prog was 3 nmol. The next measure was 7. So at 16 you're certainly in the grey area.

I suppose what I'm saying is, whether you ovulated that month or not... There are probably more coming when you won't.

So far, I actually think the extra prog is helping me ovulate - simply because my dose is low and still stimulating estrogen receptors. That's my hunch. I'm also having terrible pms... In it now. So i think ill prob need to up my prog. I think stopping ovulation might help, for me.

The jury seems to be out on how much additional prog affects your serum levels. I just cant get my head around it. So I put less emphasis, on level and more on symptoms.

I think you know what you need to trial. Why not go for it in luteal phase first - add in the extra 25mg. U could then perhaps take the 25mg all month and only take the utro in luteal phase.

In terms of troche - I found anymore than 10mg I got extreme nausea and wooziness. I do seem extremely sensitive. I couldn't get on with compounded cream at all, but I'm tolerating onas fine. It's also cleaner ingredients, so I'm happy with that. I'm sure my clinic won't be 

[Tora]

Morning Gilla, it’s great to hear you sounding upbeat!

Joziel, hope you’ve had a good nights sleep.

Have a great day ladies 🙂

[joziel]

This is all very interesting. So I had a GOOD night last night  By that I mean: I went to bed around 11.30pm and was just 'out' until 6am. I still woke up at 6am - without any jerks or jumps, just like it was time to get up. (It was still a bit early for my wake up time!)

However, I was still throbbing a little bit. It was much reduced from before this and on 62.5, but still happening a little.

So, I'm feeling good that this has improved and I actually managed to get some decent sleep. I guess I'm still worried that it is happening *at all*, but maybe it will continue to improve.

What is interesting to me, is this effect has been pretty immediate. Essentially, as soon as the estrogen has left my system. I don't know how that relates to mast cells being activated and histamine levels and other bodily processes - which I would think would take a lot longer to quiet down. So now I've no idea if all this has anything to do with mast cells and histamine at all, or if it isn't just some weird estrogen side effect.

I remained on the low histamine diet yesterday but am about to switch to my normal diet today.

I am going to remain like this now and see how things go. I might try (in about a week) to do the progesterone change, in case that leads to further improvement.

[Scampidoodle]

That’s great Joziel. So glad you slept. It can be an immediate change in symptoms if you remove the thing that’s triggering your mast cells. Like infections trigger mast cells and when the infection is treated they calm.
Mine are a bit more trigger happy these days hence get set off for longer periods 

I had a couple of good days but still getting the chest flutters. I’m in climbing Estrogen phase pre ovulation which may be impacting (I have no E to remove as not on any extra!)

I’ve had my Mirena coil for 2 weeks now and it definitely triggered my mast cells further. Hoping things calm down. I got it as the last 2 I’ve had really shut the mast cells down. Had this one quite early in a flare and my body has reacted even to that. Wish I hadn’t had it now but would cause more issues to remove it. I’m guessing the hormones are in flux.

Hope you enjoy eating normally again Joziel and you settle on the new dose. Xx

[joziel]

Interesting, scampi! Are you prone to other estrogen related things? Like heavy periods, bleeding, painful periods, breast tenderness and all that?

Have you thought about adding in more progesterone besides your Mirena coil? Only asking that because I came across this protocol from Lara Briden (based in US) who suggests adding in progesterone first during peri - and only if that isn't enough, adding in estrogen. Which would mean perhaps you could try some utrogestan by itself, not with any estrogen? See https://www.larabriden.com/rescue-prescription-menopause-perimenopause-feel-better-fast

[Scampidoodle]

Not really, I never used to have those things but I have had the Mirena since 2018.

I read that article before actually. She has quite a lot of good things on histamine and mast cells. I tried utro orally a couple of years ago and made me horribly depressed. I’ve never tried it vaginally though so might be an option. I need to try and let this coil settle first before trying something else I think. Always my first temptation to try something that might work but often get in a pickle! My histamine was high and then I got a virus end of May whjch tipped me over. Then I had this new coil early to see if it would nip things in the bud but reacted to that change in hormones too.

I’ve read that the hormones in the coil reach their stable level after the first few weeks. So I guess I’m waiting for that stable level to happen and then my body might settle xx

[CrispyChick]

Joziel - that's the approach I'm taking. Prog only. There is no support for this via the NHS. Yet, it's an approach used in Europe and the US.

[Scampidoodle]

Do you feel more settled on this now Crispy? X

[CrispyChick]

No!

[CrispyChick]

Sorry. Rubbish answer  . I've had a hard time settling in to it. My compounded cream made me sick avd woozy, but onas brand doesn't. So I've kind of restarted.

I'm full of symptoms this month, but it seems, like hrt, it takes a good few months to balance. Sigh. I e no question that I absorb... I'm getting every hormonal symptom under the sun this month 

I'm still trying. That's why I don't yet shout it across this forum. But, I would point out it's a well followed path for peri in many countries. But, at this point in my trials, I can't recommend it personally.

[Scampidoodle]

It’s true, many women swear by it. I really hope things balance out for you, it’s a good sign you aren’t feeling sick and woozy on this one though. I’ll keep my fingers crossed for you xx

[Marchlove]

The day you get it right Crispy, will be the day you start a new thread just called “SHOUT” x

[Scampidoodle]

Definitely!!! And you will get there. We all will  xxx

[joziel]

I've had an interesting realisation today. My slightly runny nose and watery eye are definitely back again, now I am on a normal diet. They have been pretty absent the last 6 days on a low histamine diet. However, they are not severe enough symptoms for me to eat such a restrictive diet  I'd rather have the coffee, chocolate and yoghurt and a runny nose, thanks 

The nighttime symptoms don't seem to be affected by what I eat.

No idea what all that means 

[Scampidoodle]

I would very much eat a normal diet if it has little impact and you can live with those symptoms. You might find a normal diet and the lower estrogen level is all you need to find balance. Keep us posted x