Hi candicet,
I would say it is definitely worth a try. At Newson their view is that much more (approx double) the progesterone reaches the uterus when taken vaginally, hence only needed every other night. Also the progesterone bypasses the liver, so that’s a plus.
I have read on here that one lady stuck with the programme for 7 months and eventually the side effects reduced to a much more comfortable level.
Remind me - are you perimenopause or post menopause? If the latter, your own hormones are still fluctuating, so a bit trickier. Ie you may be supplementing with progesterone at a phase when you own progesterone is having a bit of a surge.
The general rule of thumb is 10-12 days of 100mg vaginal utrogestan as a minimum to protect endometrium lining. Some women have therefore spaced out their progesterone intake to every 3rd day over the month, which seems to work well.
One other option used by Newson is to use cyclogest. This is a fertility progesterone, but essentially same as utrogestan. It comes in a 200mg waxy less airy. It can be cut in half to equate to the 100mg utrogestan, and has suited some women who don’t do well with the utrogestan. Some women have cut in 1/4 and therefore taken 50mg each time.
For many women, the dose of progesterone available is just too strong for their bodies, hence the trial and error of different regimen to introduce enough progesterone to protect endometrium.
I am still using trial and error ..... looking at trialling tThe cyclogest regimen next, and also investigating HRT compounded progesterone, which is available in much smaller doses, to see if I can figure out a level which works for me.
Good luck and keep us posted.