Had a check up today and gynaecological confused why I get anxiety & burning when estrogen rises. My own system has been shut down so think maybe one of the other hormones out of sync. I've always thought estrogen was the problem during meno could the balance cause this much grief?
If your system has been shut down, if I understand correctly, then your ovaries are no longer producing oestrogen nor testosterone (or is it just ovulation that is suppressed?). It is the amounts of these two hormones which are crucial not progesterone. We only produce large amounts of progesterone to prepare for pregnancy and during pregnancy. Oestrogen and testosterone are our two main sex hormones so inadequate levels of either/both will cause symptoms and of course an imbalance in favour of testosterone is also not good for women!
I am not clear why you say oestrogen is rising - as if your system is shut down I presume most of your oestrogen will be coming from exogenous source ie the gel - and relatively small amount from your body - and not your ovaries (I'm not quite clear about what shutting down actually does?). You should no longer have a cycle of any sort - I thought that was the whole point

. No other hormone will be cycling if you are not ovulating as you will not produce a corpus luteum therefore no (additional) progesterone, nor the slight rise in testosterone that occurs at ovulation.
Steep rises and falls of all our hormones can give rise to symptoms - hence the mood swings in peri-menopause - even sudden steep increases in oestrogen can have adverse side effects.
I don't really know what you are saying re the Mirena? This only provides protection for the uterus. The amount that is absorbed systemically in no way replicates the effects of progesterone elsewhere in the body - so I have read and in fact can interfere with it as well as giving rise to some negative side effects in some women - although these should wear off by the time 5 years is up ( but then is not providing uterus protection).
Hurdity x