Hi - I have been on mirtazapine for over a year prescribed due to chronic insomnia which caused anxiety and panic attacks; started on 15mg, then 30 then up to 40mg. Stopped the insomnia and the hot flushes; however, weight gain aplenty. Three months ago I started HRT and I have stopped taking the mirtazapine as I hoped by stopping I would be able to get back some control over my weight; sleeping better although I have noticed when I am anxious about something the insomnia returns; I also have hot flushes again; I am not as anxious as I am also on propranolol which I am taking regularly rather than on a "when needed" basis. Hope things improve for you. X