I've had one of those Mirena coils which add progesterone and can't say I've noticed any difference. What I can tell you having been on Prozac for several years some time ago is that my libido when on it completely disappeared. Yes, it took away the feeling of depression and anxiety, but took away any sexual feelings I had too. Now off it and suffering badly with anxiety,but not prepared to sacrifice my love life for it. At the end of the day, it depends how bad you feel and what is most important to you when making the decision to go on anti depressants. They are not the answer for everybody, but for some of us they may be a necessity.