Well from what I've read, I may change to patches. I was in so much pain and discomfort that I had to use Vagifem, although I am getting side effects such as headaches and feeling like I've taken too much caffine. I know that my hysterectomy, Taz has added to my overall discomfort, especially my bowel and they may have 'hit' my bladder in their goal to get to the uterus but I believe that I have two things going on; Vulvadynia and VA. At least with Vagifem that awful pain and urgency has gone. I went to visit my daughter and she couldn't believe how many times I needed the toilet which isn't easy to find in a big city like Melbourne. Has anyone else suffered side effects from Vagifem and if so, do they lessen after the 2 week loading period?