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HRT and Age-Related Maculopathy.


Several studies have previously suggested a relationship between use of HRT and reduced risk of macular degeneration. A report in the American Journal of Opthalmology, (Am.J.Opthalmol. 2002;134:842-848), described the results of a cross-sectional study of 394 postmenopausal women aged 50 to 78 years with age-related maculopathy (ARM), of whom 193 had nonadvanced ARM and 201 had advanced ARM. Results showed that women who had used postmenopausal HRT had half the risk of advanced ARM compared to those who had never used HRT, after controlling for known and potential risk factors.

It was concluded that HRT may reduce the progression of age-related maculopathy and that these results deserve further evaluation.

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