In the positive camp: 50 micrograms of estradot seems to be a better dose for me. I've been having awful depression every third day since I started HRT 6 weeks ago. But I upped the dose and so far so good, my mood seems to have stabilized. Hurrah. Also, no more night sweats, though I still get hot, but not to the extent of before, and the very infrequent and minimal flush, but again, nothing like before. I also don't have the brain fog. So that's all great, and I'm grateful. On the other hand, why can't I get to sleep? It's so weird. I go to bed and I'm exhausted, really exhausted. I do LOADS of exercise: one day I ran up a mountain twice and was exhausted, but I still couldn't fall asleep. As soon as I put out the light, I feel like I'm falling asleep and then PING, and for the next hour or so I toss and turn, until I give up and take a Dornomyl (french sleeping tablet, non-prescription, an anti-histamine). It works, but then the next day I'm deep asleep until 10am, which I can do as I'm freelance, but it's not ideal for work patterns. It's nearly time for my two weeks of progesterone, which may help, but I'm at my wits' end. I've always been a good sleeper and this is doing my head in. As for sleep hygiene, I never drink caffeine after 4pm, I don't exercise late at night, I don't eat late, I read before sleep, and if I do check my phone, it's in night mode (less blue light). I'm not expecting any solution, but does anyone know how the menopause does this? I know it messes with melatonin, but this seems to be some kind of trigger that's not working.