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[dangermouse]

MaryG - Do you only use the Cerazette for your prog now or do you still include compounded?

[Mary G]

dangermouse, I had to ditch the compounded progesterone because, sadly, they can't send it to EU states post Brexit.  So I use progesterone gel and 75 mcg Cerazette which is working very well.  I really liked the compounded lozenges and didn't have a single migraine for the entire time I used them but the combination natural progesterone gel and Cerazette is also working very well and it's much cheaper! 

I was using the progesterone gel interspersed with Cyclogest for a while which was also good but a bit messy.  Like Cerazette, Cyclogest suppresses FSH and LH which is essential for my type of migraines.

[dangermouse]

Thanks, makes sense!

I have never tried Cerazette and I also have the migraine issue so I am curious whether the others couldn’t suppress FSH and LH enough. Although, I suspect I would still not tolerate oestrogen but it could have helped in peri.

[CrispyChick]

Interesting ladies.

I perhaps sounded a little too positive in my post. I'm still in absolute hell. But...I feel I may no longer wish to die - which was a daily occurrence.

So, I know one cerazette is not supressing me. My FSH was in the 50s - highest it's ever been. My E was low though. So god knows where that's headed now.

I do feel I need to test this theory ahead of my hormone appointment - if 1.5 suppresses my FSH (point noted on lh Mary) and I feel a bit better - even if in agony and so fatigued - then I'll know it's the fluctuations.

Estrogen - that's a whole other ball game. It will trigger my nose pressure and MCAS reactions in me.

If could maybe do miniscule doses.

The problem is Mary, 75mg desogestral is not licenced as P part of hrt here. I doubt even an expert would agree to it. But I'm on that really scientific dose of 1.5 now  so who knows.

A lot of my reactive symptoms kick off irrespective of what hormone I add or remove. Like my stomach h is on edge now I've increased cerazette. It's bonkers. Heightened sensitivities I think.

[dangermouse]

Crispy, you did just make me laugh then, with your concern that we’re getting all carried away about the Cerazette’s success. Which, of course, we are. 

I just looked it up and can see it was in Marvelon and Mercilon pills that I tried back in the day. Felt awful on them. I did also mention Cerazette to a friend a few weeks ago when replying to another post here and she flinched recalling the horror it caused her when given it for her fibroids.

Cannot ignore MaryG’s migraine smoothing though…

[Mary G]

Crispy, re my low 75 mcg Cerazette dose, I was using one pump of Oestrogel gel plus the progesterone gel and I had a womb lining reading of 1mm.  God knows where I would have been had I taken the recommended dose of 150 mcg.  I have since increased to two pumps of gel with no breakthrough bleeding so I'll see what the next reading comes out at but after a low reading like 1mm, I think I've got some leeway.

I suppose everyone reacts differently to Cerazette and you might need more to get full FSH and LH suppression.  My blood tests came out at 0.49 for FSH and 0.07 for LH - sorry, I think your measurements are different in the UK but they are both low readings.  You might be lucky and the extra dose of Cerazette might work but it will take a few weeks to significantly reduce FSH and LH and show up on blood tests and it takes about a month for levels to rise once you stop taking it.  I found Cerazette stopped my migraine auras completely within a week.

The hormone specialist you are seeing should be able to help on this and might suggest an even higher dose of Cerazette of something else entirely.  Cerazette is very potent and should work at the right dose.

dangermouse, why don't you try Cerazette?  You can buy it over the counter in the UK and you might be pleasantly surprised with the results.  You will know pretty soon if it's going to work.

[CrispyChick]

Thanks Mary

I take it all back - having a horrific day today with hormones. Extreme agitation in morning then one of the biggest mood swings I've had ever in the afternoon - irritation and then low, teary to the point of suicidal thoughts.

So I'm guessing, 9 doses in with my extra half cerazette - it's not yet bringing down the fsh/lh and therefore the fluctuations. Dues that seem right? Possibly need a month on increased dose?

Yes. It should be potent. I think be ause I'm late peri now it's struggling to control. I guess you being post meno, maybe makes if easier.

I'll keep going. Because being on nothing or one us absolute hell.

Two was far too supressing for me. When I first started out on 2 - I tested at 4 weeks in and fsh and lh (and estrogen) were very low. So I guess 4 weeks.

Thanks for helping. X