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[CherryC]

Hi, can anyone tell me if using two patches ie Evorel 50 and Evorel 25 at the same time, should make no difference to using one patch at 75mg?
I know technically it should be the same, but does anyone have any experience of this causing an increase or decrease in oestrogen levels?
I usually use 75mg, but asked to have two separate patches (50 and 25) to allow for when I decide to try to reduce a bit (possibly over the winter).
Grateful if anyone has any info on this...

[bombsh3ll]

Theoretically the same, however potential for dehiscence around 8 edges rather than 4.

Also uses up more sites if rotation is limited.

I would ask for a 75mcg patch.

If you wanted to reduce this (and I would have a clear clinical reason to do so, not just having internalised a vague fear that estrogen is bad or dangerous), you could always cut a sliver off the edge.

[Sophya]

I actually prefer two patches. I put them on different spots so my skin gets a break, and they stick a bit better than the big 75. Hormone-wise it’s the same, at least in my case

[CherryC]

Thank you both for your interesting replies. I seem to have developed a slight headache and a slightly faster heart rate since trying the two patches, but it might just be a coincidence, as it's only been a week or two.  Will monitor and decide whether to revert to the 75 patch. I had wondered about trying to gradually reduce to 50, as I'm 64, but this really is only because I feel I ought to. I may try sometime soon and I guess can always increase back up if not successful. I am quite sensitive to hormonal changes but I imagine you need to give the body time to adjust.
Does anyone know if using a 75 patch for one change in the week and a 50 for the second change might be a way of slightly reducing overall?

[bombsh3ll]

If it were me I would keep to the same dose each time rather than using alternative doses, in order to maintain stable and consistent levels.

If there is a clinical indication for reducing then I would reduce by a small amount every few weeks.

However it is interesting that you use the word "successful" around reducing to a lower amount of estrogen.

Have you considered a DEXA scan? This can be more helpful in informing treatment decisions than simply a vague feeling that you "should" reduce it - estrogen has myriad health benefits yet is often regarded like a narcotic!

[CherryC]

Thank you for the help and advice - always good to get thoughts and experiences from others