Yes, in theory it's an equivalent dose. Changing it twice a week is correct and you say so at the beginning, then later you say 'so 100mg and then still change it once a week ' so I was just checking. Normally if you were on a 50 patch you'd increase it to 75 and only go to 100 if this wasn't enough. Some symptoms such as anxiety can be caused by both too much and too little oestrogen and increasing slowly means you don't miss the sweet spot. Some patches are indeed 100 but if you find one you absorb better you may not need this much. I find I absorb best from estradot, gel and evorel are the same and estraderm next to nothing but we're all different and you may have a different experience. Estraderm 100 are 7x7 cm and a couldn't find a patch of skin that big that didn't move when I bend, I think they're the biggest. So the advice would be to increase to 75 though if it was me I'd be tempted to put 2 patches on as that might give you the equivalent of 3 pumps gel which is probably the right dose for you if you'd stayed on gel.