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Author Topic: Utrogestan 100mg  (Read 1781 times)

Dyan

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Utrogestan 100mg
« on: August 04, 2025, 01:40:10 PM »

I am post menopause and after having a trial run off Estradol gel ( which didn’t work out) I’m now back on it, 2 pumps on my thighs each morning, along with taking 100mg Utrogestan at night for the progesterone.
I’ve been on the gel and ultrogestan 100ml for 3 days now.

It would be nice to hear from anyone on this combination of HRT, as I’ve always had the mirena for the progesterone part, and it’s a first time taking tablets.
Has anyone had this switch in their HRT treatment?

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MrsMitch

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Re: Utrogestan 100mg
« Reply #1 on: August 05, 2025, 06:39:07 AM »

Hello Dyan, I went onto that combination ages ago going from a tablet form of HRT to patches then gel/utro because neither of those worked for my symptoms.
I am on 4 pumps & 200mg utro now though.
For me it's been the best combination of HRT it really helped my symptoms particularly insomnia & flushes & night sweats. I haven't had any problems but others will probably tell you Utrogestan is one that we often seems to mean we can get spotting/bleeding etc & there are other progesterone that control that better. But its said to get the safest & therefore very commonly prescribed. I believe the mirena is far better to control that but that was not an option for me.
Don't know if that gives you the answer you need.
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Dyan

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Re: Utrogestan 100mg
« Reply #2 on: August 05, 2025, 10:44:36 AM »

Hello Mrs Mitch,

Thank you so much for your reply.
Yes that is very helpful to know you are doing good on gel/ Utrogestan.
The only thing I will say is that the first night I took the Utrogestan it didn’t make me sleep.
The 2nd night I fell asleep within minutes but woke up after about a couple of hours.
This is how it has been for the other 2 nights I’ve been on it.
I take it around 10pm.
Is this something that will get better the longer I take it? X
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MrsMitch

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Re: Utrogestan 100mg
« Reply #3 on: August 05, 2025, 11:37:44 AM »

For me it took about a month for my sleep to be more normal & in 2 weeks it was much improved. So I think time is obviously a factor. I can take mine either at bedtime, an hour before or early evening which I know isn't how the instructions tell you to take it but it doesn't make any difference for me. But I would think the time you take it is correct. It's just a patience thing, which is difficult when you've been struggling for a while, I know.
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Dyan

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Re: Utrogestan 100mg
« Reply #4 on: August 05, 2025, 11:47:03 AM »

That’s a relief to hear.
Thank you so much.
I’m a patient person but when it comes to my well being I want to feel better now🙄🤣
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MrsMitch

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Re: Utrogestan 100mg
« Reply #5 on: August 05, 2025, 01:30:23 PM »

I know, we all do. But it's very much trial & error with HRT,  it seems. I certainly had to go through a number of different types & then doses to get a reasonable result.
I'm sure you'll improve in time.
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sheila99

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Re: Utrogestan 100mg
« Reply #6 on: August 05, 2025, 02:20:40 PM »

For most people it improves sleep but for me it disrupts it yet leaves me feeling doped all day. It didn't improve, it was tolerable until day 8 after which I was a zombie. But worth giving it a bit longer as most people are fine with it. I have a mirena now and have no side effects. It might be worth you getting another one if you don't tolerate utro well.
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Dyan

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Re: Utrogestan 100mg
« Reply #7 on: August 05, 2025, 02:41:30 PM »

Thankyou sheila99

I’ve only been on it 4 days so early days yet. Just need to get my sleep 😴
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Dyan

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Re: Utrogestan 100mg update
« Reply #8 on: August 10, 2025, 11:08:53 AM »

I’ve been on the Utrogestan 100mg and back on my Estradol gel now for just over a wk.
Sleep is not great yet but I understand it can take time.
My mental health has suffered, especially my OCD thoughts, and I’m still getting bouts of really bad depression. Yesterday I had a meltdown. Hubby found me on the floor crying and in a state.
I’m taking some clonazapam to help with the anxiety,that my psychiatrist gave me for when I have a MH crisis,to get me through until my hormones get back to normal and I feel myself again.
Saying all that though, I think there has been a slight improvement. Looking back to a wk ago I felt much worse.

I wished I’d never agreed to have a trial run off my estrogen. My biggest fear was that it might impact my MH and it did, but at the time I was in a good place, so went ahead.

I just want to get back to my old self. I know it takes time so onwards and upwards.
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bombsh3ll

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Re: Utrogestan 100mg
« Reply #9 on: August 10, 2025, 02:02:16 PM »

I hope you feel better soon.

It's so sad and bizarre how women are constantly pressured to reduce or come off treatment that is integral to their physical and psychological wellbeing and stability.

I have a friend who was really highly functioning and had a career as a professional musician until she just completely disintegrated mentally around the time of her menopause. Since then she has been in and out of psychiatric hospitals and is on an absolute cocktail of drugs now, antipsychotics, lithium, you name it and nobody ever thinks about trying to reduce these even though they have made her diabetic, but heaven forbid she asked for estrogen, this is treated like a narcotic!

At least now you will be in a better position to advocate for your ongoing treatment should this be attempted again.
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MrsMitch

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Re: Utrogestan 100mg
« Reply #10 on: August 10, 2025, 02:42:45 PM »

I hope you feel better soon.

It's so sad and bizarre how women are constantly pressured to reduce or come off treatment that is integral to their physical and psychological wellbeing and stability.

I have a friend who was really highly functioning and had a career as a professional musician until she just completely disintegrated mentally around the time of her menopause. Since then she has been in and out of psychiatric hospitals and is on an absolute cocktail of drugs now, antipsychotics, lithium, you name it and nobody ever thinks about trying to reduce these even though they have made her diabetic, but heaven forbid she asked for estrogen
All those drugs will do is mask her problems & give her the idea she has permanent mental health issues that can  be resolved. It's infuriating. But your comments about them wanting us off HRT are so true. I was chatting to a lady just this morning who is now in her 80s & in terrible pain from osteoarthritis. She had a hysterectomy at 40 but was refused HRT when she was catapulted into menopause. I wonder how she'd be if she'd been taking it all these years.
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Minusminnie

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Re: Utrogestan 100mg
« Reply #11 on: August 10, 2025, 05:34:19 PM »


I have a friend who was really highly functioning and had a career as a professional musician until she just completely disintegrated mentally around the time of her menopause. Since then she has been in and out of psychiatric hospitals and is on an absolute cocktail of drugs now, antipsychotics, lithium, you name it and nobody ever thinks about trying to reduce these even though they have made her diabetic, but heaven forbid she asked for estrogen, this is treated like a narcotic!


Menopause can exacerbate existing mental health problems.
Antipsychotics are not given out lightly and for a reason.
Lithium which is a mood stabiliser often replaces any antipsychotic which might be given initially.

Agree HRT given alongside but it is not always the full answer.
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Dyan

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Re: Utrogestan 100mg
« Reply #12 on: August 10, 2025, 06:44:45 PM »

Thank you  bombsh311

I’d rather stay on it for life.
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bombsh3ll

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Re: Utrogestan 100mg
« Reply #13 on: August 11, 2025, 08:58:14 AM »

I will be on it for life too - there's no age at which my quality of life ceases to matter or at which I am willing to accept osteoporosis, which both my parents have.

I believe only a minority of the perimenopausal and menopausal women on psychiatric medication actually need it. My approach would always be to adequately restore ovarian hormones first, and then any physical or psychological symptoms that remain, that's when individual treatment for these becomes reasonable.
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Mary G

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Re: Utrogestan 100mg
« Reply #14 on: August 11, 2025, 10:53:56 AM »

Dyan, I'm on two pumps of Oestrogel every day and I split the dose by 12 hours.  I find it works very well.  I hate Utrogestan and I think it has far more side effects than synthetic progesterone.  Far too many women have problems with it and it's not particularly good at controlling bleeding.  Doctors seem wedded to it because it's natural progesterone but the virtually non existent risk with Utrogestan is only slightly lower than the virtually non existent risk of synthetic progesterone. 

I think Duphaston (dydrogesterone) oral progesterone is available in the UK now and that would probably be a far better bet for most women or perhaps Cerazette or a Mirena coil.

What is this sudden anti HRT stuff with GPs all about?  We keep hearing about doctors getting sniffly about prescribing it and constantly forcing women to reduce their oestrogen dose or have a trial at stopping it altogether.  Perhaps the NHS need to be honest with people and admit they can't support women on HRT unless they have very basic medication at a very low dose and they don't need any support.

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