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[juliaC]

Wondering if the lovely ladies here can give their thoughts

I have to stop Evorel Sequi, I'm now 55 and been on it 5 years and GP says it's no longer safe for endometrial protection. 

I currently feel I need more oestrogen but apparently that's also not safe. 


My options are to have the mirena coil and evorel patches  or  evorel conti.  I felt quite rough when I tried utrogestan vaginally once and didn't take it again so that may be out.  GP didn't like the sound of it as I felt asthmatic but it was a summer evening and could have been pollen, who knows.  I understand the concern though.

I would have preferred a higher dose oestrogen and utrogestan usage and stick to a cycle / sequential as I feel continuous progesterone doesn't work as well for me.  I seem to have much more intense prolapse symptoms and diarrhoea at times, which seem to recover on the oestrogen only, only to return again on the combined patch.  GP said with a continuous combined patch that might settle down.  Has this happened for anyone else?

Anyway, I am £100 out of pocket from sourcing private Evorel Sequi due to GP refusing it until I had a review, which I've now had and been told it's no longer an option, so I need to think quickly about what I will choose. (£100 because I had to buy 2 different ones, one to go to my place of work as I had a long distance to travel that day for a course and couldn't be without it and the other had been delayed to my house)

Interested what others would go for in this situation.  Thanks

[sheila99]

I would get a new gp. Most GPS will let you have 100mcg so if you're happy with evorel you could ask for 75 patches. If you want to stay on sequi it's your choice though they told me there's a slightly higher risk of endometrial cancer that way (in my 60s). I would try utro again as you haven't given it a fair trial - and that way you can stay on sequi even if they don't like it. I have a mirena now which I find good, no side effects and no bleeding, or you could try oral progestogens. Norethisterone is the same as in the conti patches so may suit you. Do you know if you're peri or meno? If peri I'd stay on sequi anyway, if meno it might be that increasing the oestrogen might solve the current cyclical issues.

[juliaC]

I would get a new gp. Most GPS will let you have 100mcg so if you're happy with evorel you could ask for 75 patches. If you want to stay on sequi it's your choice though they told me there's a slightly higher risk of endometrial cancer that way (in my 60s). I would try utro again as you haven't given it a fair trial - and that way you can stay on sequi even if they don't like it. I have a mirena now which I find good, no side effects and no bleeding, or you could try oral progestogens. Norethisterone is the same as in the conti patches so may suit you. Do you know if you're peri or meno? If peri I'd stay on sequi anyway, if meno it might be that increasing the oestrogen might solve the current cyclical issues.

Thanks.  I think I should maybe give utro another try and have evorel increased.  It seems the least invasive for me.  The combined patches do seem to affect me so wouldn't want to stop the sequential method yet. 

I might look at utrogestan and failing that, mirena coil.

[CLKD]

I would ask for a referral to a dedicated menopause Clinic as well as asking the Surgery what the protocol is for stopping HRT at a certain age, what R they referring to exactly.  It is cost?