Hi I’ve been using Lenzetto for 5 years and love it. I’m perimenopause and now 53. I started on one spray and worked up to 3 over a year. Symptoms stopped, then started again eventually getting to 3 pumps. To be honest I used to religiously tick box but now do it by sight (when it starts looking pathetic) which is about 2 to 3 weeks. So probably way over the time I should. I haven’t noticed any disparity in symptoms at any time. I worked on the basis that if I wasn’t getting enough my body would tell me and I guess our natural hormones weren’t dose measured either. Maybe I’m lucky and not super sensitive to the amount.