Hello ladies,
I have been on pregabalin for some years now, and yes you can gradually up the dose if that suits you better, initially I felt like a zombie on the morning dose, so I have mine lunch time and evening, I couldn't tolerate gabapentin, like you I'm very sensitive to meds and even changing hrt dosage can be too much, some people are just hypersensitive to medication, if this is the case I would start with a low dose and slowly increase until you feel stable at that dose,
Hope you feel better soon
X