That's quite a low dose of estrogen and you don't mention any androgen replacement, which can also be really beneficial for mood and motivation.
That's where I'd start.
Micronised progesterone can impact mood negatively, even when taken vaginally, and if this is the case there are multiple other options.
However the timing of these issues can indicate whether it is related to the progesterone or not - if you felt this way before starting the progesterone, or it only came on long after you started it, then it probably isn't that, but if it coincided then it may be worth a short break (eg 2-4 weeks) from the progesterone to see if this makes a difference.
I personally am not a fan of antidepressants, and most people I know who take them really don't seem very happy. I recognise that for some people they can be helpful but I believe they benefit far fewer people than we would like to think. Like any medication they are also not free of risks, for example increased falls and fractures, so it is important to evaluate the net benefit in each case rather than just parking people on them indefinitely for vague indications with no exit strategy and often no medical follow up. This happens more to midlife women than any other demographic.
I would therefore question whether the fluoxetine is serving you given how you are currently feeling despite taking it.
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Topic: Any comments appreciated been on hrt years on utrogestan 100 mg use vaginally in (Read 1984 times)