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Menopause Matters magazine ISSUE 81 out now. (Autumn issue, September 2025)

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Author Topic: Anxiety and insomnia during withdrawal bleed  (Read 2233 times)

AnderH

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Anxiety and insomnia during withdrawal bleed
« on: March 14, 2025, 07:13:38 PM »

Hi everyone,

I’m 44 and have always suffered from anxiety but was managed over past 8 years on 20mg of citalopram. Four months ago I had an anxiety attack out the blue which led to ongoing anxiety and insomnia, worse during and after my periods which are still regular but on a shorter cycle. Went to GP and my citalopram was increased but I continued to have an anxiety ‘crash’ during my periods. Gp started me on HRT three weeks ago, 50mg Evarol patch and 200mg Utrogestan for two weeks on then two weeks off. I felt much better when started the patch and Utrogestan and my anxiety and sleep really improved. I started having period a few days before I was due to stop the Utrogestan and had period, my anxiety and insomnia came back day after I stopped the Utrogestan. I’m wondering if I can take the Utrogestan every day or if I am likely to always have this crash during the withdrawal bleed if still having my own periods. Sorry for the long post, I’m just really struggling with this bad anxiety! Xx
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bombsh3ll

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Re: Anxiety and insomnia during withdrawal bleed
« Reply #1 on: March 15, 2025, 11:57:59 AM »

You do realise that both periods and withdrawal bleeding on exogenous hormones are entirely optional don't you?

If you feel better with a stable daily dose of estrogen and progesterone, why not just take it continuously, every day? Withdrawal bleeding on menopause hormone therapy or the pill is not medically necessary, it is a relic from a very paternalistic era in women's healthcare when it was believed that women ought to be given an artificial menstrual cycle otherwise they would think they were pregnant.

(Note the dose is usually halved if taken continuously vs cyclical, but doesn't have to be if the 200mg is providing clinical benefit.)

Now if you are still having your own periods, the micronised progesterone is not strong enough to get rid of them, so you would probably continue to bleed. This might be less regular than what you presently have. However you may feel this is worth it if your mental health is better on continuous.

Alternatively you could use a combined oral contraceptive pill taken continuously for menstrual suppression - this is what I use myself and have been bleed free and hormonally stable for many years. I am 45 and have a much better quality of life than others my age who are riding a hormone rollercoaster and bleeding all over the place.

If a combined pill isn't for you, there are also suppressive progestins like desogestrel or slynd that can shut your cycle down and allow you to take transdermal estrogen alongside this.

Some women can even achieve amenorrhoea on a single dose of the mini pill desogestrel which can be taken alongside estrogen and micronised progesterone.

So you have tons of options, and you absolutely do not have to put up with your current situation.
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AnderH

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Re: Anxiety and insomnia during withdrawal bleed
« Reply #2 on: March 15, 2025, 02:51:03 PM »

Hi, thank you so much for this info, it is really helpful, and I will go back to my GP to discuss my options!
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sheila99

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Re: Anxiety and insomnia during withdrawal bleed
« Reply #3 on: March 29, 2025, 12:47:15 PM »

As above, utro is unlikely to stop your periods as you still have a cycle of your own but it might be an option to use the 25/28 cycle where you have a 3 day break to allow for a bleed. A mirena would be another option to be bleed free. For most people utro helps with sleep, the other progestogens usually don't.
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