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[Tinybutmighty]

I was on 3 pumps of Oestrogel per day but feeling awful with a level of 90pmol/l so increased my dose to 4 pumps.   Recent bloods show that my oestrogen level is still only around 250 pmol/l.  I understand I should now be taking 3 x 200mg Utrogestan cyclically for 4 pumps of gel. My question is if I’m not absorbing oestrogen well does this mean at 3x100mg Utrogestan my progesterone will be too high?   Feeling rubbish on 3, with horrible heartburn, bloating and constipation.

[jillydoll]

Hi

I’m on 4 pumps of gel, but I take, and have been told to take 200mg Utrogestan.
Maybe your hormones are out of sync and too much progesterone.

[bombsh3ll]

Guidelines say progesterone dose should be increased proportionate to estrogen dose.

Common sense says progesterone dose should be proportionate to amount of estrogen actually getting into the body. I know this is the opinion of Louise Newson and it is one I share.

So if somebody was on half a pump and had an estradiol level of 250pmol/L they would only be on 100mg continuously or 200mg cyclically. Then there is you on 4 pumps who also has an estradiol level of 250pmol/L plus clinical evidence of hypoestrogenism.

If that were me, I would take the lower dose of progesterone. You can get a private scan yearly to be on the safe side, in fact I believe this is a good idea generally.

Also "higher dose" progesterone is 300mg cyclically, not 600mg cyclically. So if you are taking 3 x 200mg it's no wonder you feel like crap unless that's a typo.

You could also consider taking it continuously unless there is a good reason for being on cyclical - if you wanted to play it safe at least that would only be 200mg every day.

[Tinybutmighty]

Thanks for the input. Yes it’s a typo I’m taking 3 x 100mg currently not 200. But I still suspect it’s too high in relation to the amount of oestrogen I’m absorbing.  I have a GP appointment next week so shall discuss it then.  Actually hoping to get an increase to 5 pumps of gel. Definitely feel better on 4 than I did on 3 but still not optimal, almost feel I’m teetering on the edge of  symptoms returning

[joziel]

Tiny, your GP may not want to increase above the licensed dose - which is 4 pumps. If that happens you can either try the max licensed dose via another product like patches or you would have to go to a menopause clinic to get over the licensed dose approved.