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I use mine all times of the day and night. I’m on twice a week though so it’s just when I remember but doesn’t seem to make a difference and they never fall out.
I use it at bed time now, after I popped one in before going to work and didn’t realise it had fallen out when I went to the loo at work and didn’t get flushed away and someone used the loo after me and shouted out that there is a little white tablet in the loo.I did admit it was mine and what it was for😳
I have always inserted at night after my bath, laying down, reading. It has all night to be absorbed. Let us know how you get on?
I didn't find that Vagifem alone was having any effect on the outside and requested Estriol cream, one tube will last me three months or more as only a tiny amount is required, both treatments work very well together with the added help of Yes moisturiser. But give it time and see how it goes.Just to say that I am not on systemic HRT, the reason perhaps why I need more topical treatment.
I find that KY Jelly or estriol smeared round the dry, itchy outer labial area helps. Regular use of estriol inserted with the applicator every 3/4th night keeps my symptoms under control. Otherwise peri/menopause thus far has been reasonably uncomplicated.