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Menopause Matters magazine ISSUE 81 out now. (Autumn issue, September 2025)

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Author Topic: Is estrogel too high??  (Read 1021 times)

warwick01

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Is estrogel too high??
« on: February 11, 2025, 11:09:27 AM »


Morning ladies,

Just looking for some advice. Not been feeling great recently, wondering if I am absorbing new oestrogel as it seems weaker. Just got bloods back and estrogen is 400 usually been around 300. I'm 66 post meno. Is this too high ??
Thanks
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Mary G

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Re: Is estrogel too high??
« Reply #1 on: February 11, 2025, 12:07:13 PM »

That is strange because for me it's the other way around!  How many pumps are you using and what type of symptoms are you having now?

I always thought 300 was a good number to aim for post menopause and it's enough for bone protection but my migraines resurfaced so I have had to go back to two pumps of Oestrogel. 

400 is definitely not too high but if you don't feel well, can you revert back to the original gel? 
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warwick01

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Re: Is estrogel too high??
« Reply #2 on: February 11, 2025, 02:32:11 PM »


Hi
Currently on 3 pumps. Not sure why I feel off. Increase in panic/anxiety the problem. I ways was around 300 so may be I will go back to 2 and hopefully it will settle. At least I know I am absorbing the gel, even thought it feel more watery

Thank you 😊
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bombsh3ll

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Re: Is estrogel too high??
« Reply #3 on: February 11, 2025, 03:15:58 PM »

It can be hard to get an accurate blood estradiol level on gel as there is a sharp spike after applying which quickly drops off, so depending on the time of day you take the test the result can vary widely.

I am on oral estradiol (Zoely) and my level is consistently around 400pmol/L although a small amount of this will be my own as I am 45.

This is the level I plan to maintain for the rest of my life as it is where I feel well.

300pmol/L is the absolute minimum I would personally accept for bone health based on Professor Studd's work.

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joziel

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Re: Is estrogel too high??
« Reply #4 on: February 11, 2025, 05:50:49 PM »

No, that isn't too high. In fact, most women do best between 450-650pmol according to a lot of the research.

My own estradiol is between 650 and 880pmol and I need it there, for my symptoms.

So no, that is not a high E level. It will only help protect your bones better!
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warwick01

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Re: Is estrogel too high??
« Reply #5 on: March 02, 2025, 11:33:07 AM »

Thanks ladies xx
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