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[GalwayGirl]

Hi all
I have been having horrific peri and have struggled with both hrt and ADs - very unstable mentally and even worse since stopping ADs that were making me feel awful. I am now on 75mcg estradoit after much tinkering on gel but I feel it is way too strong. When I change it I seem to go completely crazy it’s very frightening and I have developed new significant facial hair and cannot sleep- sleep also linked to depression no doubt. I cannot speak to my clinic until new year and a friend suggested I keep it on a little longer until I can to avoid this feeling of overload. I have lots of pain too and struggle with progesterone so all a bit of a mess. Whilst I won’t take this as medical advice has anyone any experience of doing this and an idea on what would sensible to calm down the intensity and not meddle too much ? Thanks x

[CLKD]

Many find the progesterone part of a regime difficult to tolerate.  A few find it helpful.

Keeping a mood/food/diary mayB of use.  Do U see a dedicated menopause clinic?

 

[GalwayGirl]

Thanks yes I do- Newson. I think though 75 is too much for me and the progesterone can sometimes be great but too much and I’m in a terrible state. My main concern atm is seeing if i can change patch a little later

[CLKD]

Sorry can't help.  MayB put the product name into the search box to see if there are threads to read?  Make notes ;-)

[bombsh3ll]

If you want stability you need to change the patch when it is due at the latest, ideally 3 days if yours stick that long, but certainly no more than 4.

When women try to eke out their patches, wearing them longer than the recommended interval, which usually happens as a result of affordability issues or product shortages, they end up with very unstable estradiol levels as that patch stops working reliably and levels plummet.

This can result in a worsening of symptoms, unscheduled bleeding, and for some the impact of a sudden upward swing when a new patch is applied.

Please try to maintain stable levels by being consistent with both your estrogen and if relevant, the progesterone.

Individuals with mood instability can find continuous progesterone easier to tolerate than seesawing up and down.

75mcg is not a high dose unless you are a super absorber. It is not higher than what you would have routinely seen during your menstruating years.

Facial hair can also be a sign of low estrogen relative to androgens, with resultant low SHBG, so more of your testosterone is unbound.

You are lucky to have access to Newson's clinic. I would keep things consistent until you see your provider.

A blood test may also help reassure you that you aren't overtreated.

[GalwayGirl]

Thanks so much and all noted - I can’t help feel it is too strong as it hits me on day 1 but I’ve also messed up with the progesterone this month and it’s all made ne really quite unwell mentally. So hard to know how all this will end !