Hi, I am 43 and have been using vagifem for nearly a year. I use it every other night. It has really improved the soreness and itchiness however, I am still struggling with dryness, no sex drive, issues with arousal and sexual dysfunction with orgasm. I have had multiple UTIs and have an irritable bladder. Sex causes UTIs as well. Touch on my skin generally almost feels sore/annoying and not sensual. I have a right sided headache most of the time accompanied by constant tinnitus and low level trigeminal neuralgia. My periods come every 20 days and I swing between feeling depressed and anxious. I experience palpitations and random chest pains. I suspect all of this is related to my hormones. I do also have a thryroid problem but this is well treated. However, I don't get hot flushes but do have trouble getting warm or feeling warm sometimes. I ran some hormone tests a while back and my progesterone was very low and estrogen OK but on the lower end of normal. My GP seemed to want me to hold out from taking more HRT about a year ago. Should I be doing something else before I go down the route of requesting something stronger? I am quite young so am worried about how long I can use stronger HRT for? Thanks to anyone who responds to me.