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[PK39]

Hi,
I have tried the meirna coil and did not get on with it. Just finished my first 14 days on geptrix (like Utrogesten) two tablets at night. It has not agreed with me at all. I felt very emotional, dizzy, nauseous. It was bad enough one day I could not work and could also not take my children to school.
I am just feeling disheartened and not sure what other options there are. I use two pumps of oestrogel and that’s really been helping symptoms.
Does anyone have any advice?
Thank you

[CLKD]

 

I don't use HRT so can't really help but I do know that many have problems with the progesterone part of a regime.  What was 'wrong' about the Mirena?

[bombsh3ll]

There are multiple other options, have you considered any of the oral progestins such as desogestrel, drospirenone, norethisterone, dydrogesterone (available in oral combination) or medroxyprogesterone acetate?

There's also the combination patch with norethisterone.

Also if you are under 50, (under 55 with no risk factors if treated privately) the combined pill taken continuously can be a better option as this stops bleeding and hormonal fluctuations.

[PK39]

Thank you I will talk to my doctor about this. I have never gotten on well with hormonal contraception, so I am not too sure how well I am going to get on with HRT to be honest but still early days.

[bombsh3ll]

The most important thing to know is that there are multiple options, so don't feel stuck if the first couple haven't suited you.

Don't forget about tibolone as well if standard hormone therapy doesn't work out.

[tnshoe]

I have had better results using progesterone vaginally, which was recommended to me by my doctor. Don't give up! Keep researching and asking for options that work for you!

[sheila99]

I would try it vaginally before asking to change. It's the same dose, just push it up as far as you can.

[Angieyy]

Hello I am only 5 weeks in and have had some issues with low mood and anxiety the doctor advised me to change the way I was taking the progesterone. 100mg utrogestan

I was taking it vaginally throughout for 1-25 days with 3 day break I would say day 20 was when I started having problems.

I have now been advised to take it every 13 weeks for 14 days only

I will be honest this concerned me just because Iv'e not heard of it before being taken in this way, but I did check the NICE guidelines and it said this was ok to take it this way.

[sheila99]

Hello I am only 5 weeks in and have had some issues with low mood and anxiety the doctor advised me to change the way I was taking the progesterone. 100mg utrogestan

I was taking it vaginally throughout for 1-25 days with 3 day break I would say day 20 was when I started having problems.

I have now been advised to take it every 13 weeks for 14 days only

I will be honest this concerned me just because Iv'e not heard of it before being taken in this way, but I did check the NICE guidelines and it said this was ok to take it this way.

This isn't safe and I don't believe the NICE guidelines say it is? A sequi regime is 2x100mg x days days per 28 day cycle. If you're going to use a 3 month cycle it's really important to get scanned periodically so you have some warning the lining might be reaching a dangerous thickness.

[Angieyy]

I will double check but i'm sure I read it is as I checked straight away on their website as I was unsure about it.

off to check now 

[Angieyy]

Three-monthly cyclical regimen — oestrogen is taken daily and progestogen is given for 14 days every 13 weeks.

For perimenopausal women, monthly or 3-monthly cyclical regimens may be used.
A 3-monthly regimen may be more suitable for women with infrequent periods or who are intolerant to progestogens. See the section on adverse effects for more information.

This is what is on their website

 https://cks.nice.org.uk/topics/menopause/prescribing-information/hormone-replacement-therapy-hrt/

Thanks

[Angieyy]

I agree that a scan should be given before and maybe after a 6 months, it has left me feeling uneasy

[bombsh3ll]

It also depends on the dose of estrogen.

I totally agree with scanning if on a reduced progestogen regime - actually I believe all women over 40 or so should have a pelvic ultrasound every 1-2 years as part of routine well woman screening - however if someone is only on a very low dose it is less of an issue.

Additionally, the studies that have shown endometrial safety with 3 monthly progestogen all used synthetic progestins which are much more potent.

I am not sure that long term endometrial protection has ever been demonstrated when micronised progesterone is taken every 3 months.

[sheila99]

I can't see the link as it's UK only and I'm in Mexico atm. Last time I looked (might have been a year or two ago) the 3 monthly cycle was referring to tridesta which is designed to let you bleed once in 3 months, not the 'normal' sequi regimes which are designed for a monthly bleed.

[Penguin]

I can't see the link as it's UK only and I'm in Mexico atm. Last time I looked (might have been a year or two ago) the 3 monthly cycle was referring to tridesta which is designed to let you bleed once in 3 months, not the 'normal' sequi regimes which are designed for a monthly bleed.

I've looked at the link and it doesn't mention a specific progesterone  but I agree, I was also of the understanding it was only tridesta.