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Author Topic: Change from sequential to continuous issues  (Read 813 times)

Mumof3

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Change from sequential to continuous issues
« on: September 29, 2024, 05:22:51 PM »

Hi,

I’ve been on sequential HRT of 3 pumps Oestrogel & 200 Utrogestan for 14 days per 4 weeks for about 2 years and all was well except for some irregular bleeding - I had bleeding, just could be any time of the month & wasn’t linked to finishing the Utrogestan.

My GP suggested moving to continuous back in April, with 3 pumps & 100 Utrogestan daily. Since then I’ve gained around 1.5 stone & my mental health has taken a dive. I feel irritable & emotionally numb a lot of the time.

I know the evidence says HRT does not cause weight gain but I’m sure it’s the cause as nothing else has changed. I’ve got an appointment with my go this week to discuss returning to sequential but just wondered if anyone else had experienced similar issues?

Just for context, I’m 48.

Thank you x
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sheila99

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Re: Change from sequential to continuous issues
« Reply #1 on: September 29, 2024, 06:03:26 PM »

I'm 63 and still on sequi because of utrogestan side effects (poor sleep and doped all day). They told me there's a slightly higher risk of endometrial cancer this way but for me the risk is worth it to have time off utro. At 48 there's a good chance you're not meno yet anyway. Utrogestan has a sedative effect, that's why it helps with sleep and it could be why you feel emotionally numb.
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Primrose

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Re: Change from sequential to continuous issues
« Reply #2 on: September 30, 2024, 04:59:23 PM »

Hi Mumof3,

I just read your post after I started a new chat regarding a change from Sequential to continuous HRT albeit my post references patches - sorry x

I have issues with bleeding and spotting at the minute and have been told to expect this for upto 6 months but it is my mental health which has changed so quickly too which is upsetting me.

I switch from feeling happy, to crying at almost anything to feeling emotionally numb to raging fury all within a very short time span.

I am so sorry you are not feeling great, I hope my reply helps. I feel confused, have brain fog, oh and when I do sleep I have dreadful graphic nightmares.

I don't want to use words which upset others so please forgive me but there are days when I feel totally crazy or indifferent almost unable to control the changes in emotion and this is worrying.

I feel my and perhaps your changes are hormone related but I am no expert.  All I can say is before the switch I was doing ok.

I am seeing my GP a face to face appointment next week (amazing). Maybe a decent chat with an understanding GP might be useful.

I hope you start to feel better x
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Mumof3

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Re: Change from sequential to continuous issues
« Reply #3 on: September 30, 2024, 07:20:49 PM »

Thanks both for your replies. I’m really sorry Primrose that you’re feeling so unwell on continuous. Initially I thought it was just coincidence that I was feeling so bad but I went away in August & forgot my Utrogestan so had 2 weeks off it. Within a few days I felt so much better and then the same fog descended when I started it again after we got home & has stayed.

I’m seeing my gp tomorrow and think I’m going to ask about going back to sequential. Interesting that I didn’t have these issues on sequential & actually looked forward to my 2 weeks on Utrogestan as it helped me sleep!

Probably just goes to show, if it’s working don’t change it! 
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CLKD

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Re: Change from sequential to continuous issues
« Reply #4 on: September 30, 2024, 07:29:26 PM »

Yep.  Why did your GP decide you alter your regime Mumof3?

Hopefully your GP will have time to listen and advise.  Let us know!
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