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Author Topic: Progestogen - what next?  (Read 490 times)

sheila99

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Progestogen - what next?
« on: September 14, 2024, 05:34:21 AM »

6 years ago I started hrt on evorel sequi. I had no side effects on the conti patches but developed an allergic reaction to the glue. I've been on sequi utrogestan and gel/patch for the last 5 years. It isn't great (by any route), disrupted sleep and sedated all day. There is no way I'm taking it continuously. Tried a mirena but the cervix wouldn't open so they couldn't get it in (perhaps I had a lucky escape). Changed to noresthisterone with the aim of a conti regime. Now on day 8 and sleep is getting progressively worse, it's gone from waking up at 6 am to 3.30. Also not impressed with the 5mg dose when only 1mg is needed or the increased risk of clots and liver problems.
  What is the shortest period I can take it for to ensure a bleed? Not sure how much longer I can last.
 What next? Any point trying anything else or it back to utrogestan?
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Dotty

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Re: Progestogen - what next?
« Reply #1 on: September 14, 2024, 06:23:52 AM »

Hi instead of taking 5mg of norethisterone you can take 3 tablets of Noriday ( mini pill) which is 1.05mg.

Page 7 of this document …

https://thebms.org.uk/wp-content/uploads/2021/10/14-BMS-TfC-Progestogens-and-endometrial-protection-01H.pdf
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CrispyChick

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Re: Progestogen - what next?
« Reply #2 on: September 14, 2024, 08:43:26 AM »

The new Slynd pill is now BMS approved as the progestin part of hrt.

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Hurdity

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Re: Progestogen - what next?
« Reply #3 on: September 14, 2024, 08:56:58 AM »

Have you tried Provera, since you are happy with trying synthetic progestogens? It is apparently excellent for endometrial protection. As an aside my local gynae GP didn't like the idea of norethisterone in older women due to stroke risk which was also mentioned recently by Dr Currie, though I haven't seen the studies so the absolute risk may still be very low.

Hurdity x
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