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[joziel]

Seasidegirl, you say "it then seems to vary how many days I can take 200 before I get a racing heartrate, difficulty sleeping, jitteryness, irritability. "

These are all low estrogen symptoms for me. They might be happening at one part of your cycle more than another just because of what your estrogen and ovaries are doing then, nothing to do with progesterone.

I would be trying to get your estrogen higher, if I were you, and see if that helps.

[Seasidegirl]

Seasidegirl, you say "it then seems to vary how many days I can take 200 before I get a racing heartrate, difficulty sleeping, jitteryness, irritability. "

These are all low estrogen symptoms for me. They might be happening at one part of your cycle more than another just because of what your estrogen and ovaries are doing then, nothing to do with progesterone.

I would be trying to get your estrogen higher, if I were you, and see if that helps.

Thanks Joziel, I'm coming to that conclusion having read comments here.   I was convinced it was the P but it isn't making sense. 

I had a treatment plan to go from Estradot 50 to 75 but I hadn't particularly felt the need to consistently, I've added the extra half patch today and I'll keep it up until the next round of P and see if that helps. 

I'm also waiting for a thyroid blood test,  I have borderline hyperthyroidism and I wonder if that's possible an issue too and it seemed sensible to rule that out.

It is all so confusing!   Thank you so much for your advice. 

[Hurdity]

There is stuff out there to suggest that women that suffer pmdd aswell are actually low in progesterone so hopefully it would cause any severe problems.

Hi Emjay

Just wanted to ask about that comment as I haven't heard of this? I understand pmdd is more to do with either low oestrogen and/or the dramatic fall in oestrogen that occurs in the week or so leading up to the period, and in addition either progesterone intolerance, as it is released during the second half of the menstrual cycle, and/or the progesterone withdrawal which occurs at the end of the cycle, just before the bleed and is associated with its own negative symptoms. As far as I understood, women who suffer this debilitating condition, usually feel much better during the first part of the cycle, once the progesterone withdrawal is over, and this (first part of cycle) is when oestrogen is rising and reaches a peak around ovulation - so this is when progesterone is at its lowest.

If you have any research to the contrary I would be really interested to read it.

All the best anyway!

Hurdity x