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[kittydaydream]

Hi ladies, just wondered if anyone else had a horrible experience on Provera? I took the 1st one the night before last and yesterday I had awful symptoms….keep thinking I’d throw up, felt drugged, palpitations and anxiety! I’m peri and was on Utrogestan but had lesser but still yuk symptoms on that! I’m waiting for an appointment for Mirena at mo!

[CLKD]

How long B4 U get the Mirena coil?  If any medication makes me feel that ill, I stop.

MayB put provera into the search box and read the threads?  Make notes ;-)

[kittydaydream]

I might have to wait a month for mirena and I’m worried about thickening of the womb, but utro and Provera are awful for me!

[joziel]

Go back to utrogestan if you have any left. Have you tried taking it vaginally and rectally?

[kittydaydream]

I tried utro vaginally but it still makes me feel awful 😢

[CLKD]

 

[oldlady1961]

Hello I had a really bad reaction to provera. I was supposed to take it (5mg three times a day) for 4 months after PMB and biopsy showed too much thickening. I lasted 9 weeks and put myself back on utrogestan but 200mg instead of 100mg. This is in the British Menopause Society guidelines as being fine for endometrial thickening. No idea why my consultant didn’t just suggest that in the first place, as I was totally happy before on Oestrogel and 100mg Utrogestan, instead of suggesting this synthetic progesterone which turned out to be poison for me. Have had repeat biopsy and endometrium is now fine so it worked.  But some effects of provera are still there 16 weeks after my last dose. It seemed to put me back to the beginning again as if Oestrogel no longer worked. I had the whole range of symptoms and bitterly regret not stopping it immediately. Hot flushes. Cold chills. Insomnia. Heavy night sweats. Anxiety. Panic attacks. Anorexia (the only silver lining is I lost 22lbs as I couldn’t eat and I needed to lose it!) Blood tests (private of course my GP has barely heard of “menopause”) show I am still absorbing Oestrogel and I am hugely improved so it is possible to reverse the effects. I am also now on Androfeme but it’s too early to see if that’s working yet.

[bombsh3ll]

Have you already got a thickened lining or is this just for general endometrial protection?

Provera or utrogestan are not your only options whilst waiting for the IUS.

You could try norethisterone, 150mcg desogestrel (off label but supported by the BMS) or slynd.

If under 50 (or low risk and under a private specialist) a combined pill with estradiol and a kind progestin can be a great option.

If you are post menopause, tibolone is another alternative for progesterone intolerant women that is often overlooked.

[kittydaydream]

Old lady 1961 - I’m in peri and opted to have mirena out in April as I was having anxiety and thought Utrogestan might help! HUGE mistake! Anxiety was manageable before but after 3 months continuous utro i suddenly had disturbed sleep waking like having had no sleep and with terrible anxiety! Then the one Provera I took was even worse! I swear I hate this time in my life, everything stopped, I don’t see anyone and don’t have motivation to do anything! I’ve been trying to get an appointment to have mirena again but it’s not happening quickly!

[kittydaydream]

Have you already got a thickened lining or is this just for general endometrial protection?

Provera or utrogestan are not your only options whilst waiting for the IUS.

You could try norethisterone, 150mcg desogestrel (off label but supported by the BMS) or slynd.

If under 50 (or low risk and under a private specialist) a combined pill with estradiol and a kind progestin can be a great option.

If you are post menopause, tibolone is another alternative for progesterone intolerant women that is often overlooked.

Hiya it’s for protection, I’ll ask dr for another option for progesterone but as for a combined pill I’m too terrified to change anything else in case I’m even worse! Also Off course you’re stuck with three month chunks of time where you have to wait to see if it’s better or worse! Honestly I’m just totally fed up and frightened all the time that I’m going to die 😞

[kittydaydream]

My oestrogen was 388 last month so I’m also wondering if my 100 patch is too much and I’m debating cutting it in half? What you all think?

[oldlady1961]

I’m so sorry for you it’s sounds so awful and I definitely know something of what you’re going through.

My serum oestrodiol is higher than yours at 471 pmol/L on two pumps Oestrogel per day and I was told that’s fine - have you been told 388 is too high? Although I am 63 and it was suggested that once I feel normal again (I’m definitely getting there but not yet) I could start to try to reduce as I may not need this much at my age. The reason for considering a reduction is because of the PMB and trying to prevent that happening again.

[joziel]

If you feel well and your estradiol is 388, that's totally fine. I feel like shite and can't sleep and mine is 325pmol, so I'm aiming to get up to 450-650pmol.

Estrogen is very safe, very good for your health, anti-inflammatory, and nothing to be afraid of if you have sufficient progesterone on board.

[kittydaydream]

Oldlady1961 - thank you! I’ve not been told 388 is too high just that it’s on normal range!

[kittydaydream]

Joziel- I too feel like shite, problem is the gynaecologist I see won’t go above 100 patch, I’ve got estrogel so could add that but then I’d be in trouble when I run out! I guess I could stick on another half or quarter patch?