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[Lisasmith]

Does anyone take 200mg progesterone, vaginally, continuously? This is what I’ve been advised, but when I google, it says taking it vaginally is off label, so I’m concerned it isn’t tested fully, and may not be as safe as taking it orally? Taking 200mg orally is too much for me, and if I take only 100mg I have on and off heavy bleeding. For context I’ve been on HRT about 8 years - had no bleeding with the Mirena but I don’t want another of those.

[CLKD]

 

hopefully some1 will be along. However, many medicines are offered 'off label' because they have been found to work.

[sheila99]

It seems to be a licensing issue rather than a medical one. In the rest of Europe utro is licenced for hrt orally and vaginally. In the UK it's  licensed for hrt orally but ivf vaginally.

[Polpringle]

I’ve been using 200 continuous vaginally for the last 2 weeks without a problem I  insert one about 3pm and the other at bedtime, obviously as it’s off licence I have no idea if that’s ok but so far it’s working for me

[bombsh3ll]

I used utrogestan vaginally 12 years ago during IVF and only heard of it being used orally much more recently when I became interested in menopause.

I couldn't believe people were swallowing the same capsules that I used to stick up my chuff.

It has been used this way for years and if it were at all unsafe it wouldn't be used in IVF and early pregnancy.

If it works for you that's great.

[Cassie]

I thought it was 100mg used continuously and vaginally is fine, if it doesnt cause you irritation. I prefer it this way. 200mg daily is a very strong dose how much oestrogen are you using?

[Polpringle]

I thought it was 100mg used continuously and vaginally is fine, if it doesnt cause you irritation. I prefer it this way. 200mg daily is a very strong dose how much oestrogen are you using?

I think it’s the new rules of 4pumps and upwards 200mg is needed, that’s what my dr said

[bombsh3ll]

I was on 200mg three times a day from the embryo transfer until the end of the first trimester.

It didn't cause me any problems at all and is widely used in this manner for IVF.