Sorry you’ve had a rough time.
Sore boobs may be high oestrogen but might not assume that on 50 patches.
Best to get some blood tests rather than guessing.
Also patches often drop after 3 full days so worth changing every 3 (instead of twice a week /3.5/4) in case that’s causing fluctuations.
Do bloods on same patch day, ideally day 1.
Meantime, my consultant suggested evening primrose oil - I was sceptical but it did help a bit.
For me, sore boobs were too much e2 (300 patches, levels way over 1000 with crazy fluctuations).
Hth xx