Penguin,
The estrogen risk is going to be different for every woman, based on history and lifestyle, modifiable risk factors, etc. Obesity and diabetes are significant factors. For example, an obese woman may need a higher dose or different progestogen to adequately protect her uterus.
Interesting facts:
"Obesity in young adulthood is positively associated with risk of endometrial cancer, even after accounting for body mass index (BMI) in adulthood.
Young adulthood obesity is most strongly associated with risk of endometrial cancer among endometrioid subtypes, those who were pre/perimenopausal, non-Hispanic White and non-Hispanic Black, among never hormone replacement therapy (HRT) users and non-diabetics.
Weight gain over the life course is also positively associated with risk of endometrial cancer, whereas weight loss is inversely associated."
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Topic: Do you have to go from sequi to conti? (Read 6145 times)