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Author Topic: Sensitised to utro - running out of options  (Read 6261 times)

Banjo1973

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Re: Sensitised to utro - running out of options
« Reply #15 on: November 21, 2023, 08:20:04 AM »

Crazy vivid dreams are deffo a utro thing.

I have always had very light periods all my life. Short (3 days) and very little blood (often no flow at night when I'm horizontal)

Now I take utro, should I expect them to be heavier?
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Peri2022

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Re: Sensitised to utro - running out of options
« Reply #16 on: November 21, 2023, 09:52:44 AM »

Ah sorry Banjo, I think maybe I wasn't clear about the utro/period connection! To clarify: my periods (pre HRT) were always incredibly heavy and painful, lasting about 10 days. Because progesterone keeps the uterine lining nice and thin, and utrogestan is progesterone, it tends to make people's periods lighter and shorter, as has been the case (thankfully) for me.

What I meant was, I wonder if using utro rectally will help the drug to be absorbed as well as it has been vaginally. If it doesn't absorb as well, then I would expect my period to be heavier again because the drug hasn't been keeping my lining as thin as it should.

So if anything, one would expect your periods to get even shorter and lighter on utro, as long as the drug is being well absorbed.

Sorry to add to the general confusion - I hope that's a bit clearer!
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Banjo1973

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Re: Sensitised to utro - running out of options
« Reply #17 on: November 21, 2023, 01:29:41 PM »

Thank you, that was helpful.

Fingers crossed my womb lining is nice and thin.

I'll let you know how I get on x
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Hurdity

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Re: Sensitised to utro - running out of options
« Reply #18 on: November 22, 2023, 08:27:39 AM »

 Hi again Peri2022

I responded to your post abut using Utro rectally and about things you mentioned, earlier in this thread but I don't think you have seen it because you continue to refer to utro rectally etc in your discussion with Banjo and whether it's "legit". I hope my comments were/are helpful and shed some light on this.

Hurdity x
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Peri2022

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Re: Sensitised to utro - running out of options
« Reply #19 on: November 22, 2023, 09:36:44 AM »

Hi Hurdity. Yes sorry I did see your message - in one of my posts I explained that the irritation is just internal rather than external - interestingly, as far as rectal progesterone being legit, I listened to a Newson podcast yesterday where they discussed the absorption benefits of taking prog vaginally or rectally as opposed to orally. Certainly it’s off license but Newson appears to endorse it…

Anyway, as an update, I used it rectally again last night but didn’t sleep well at all. Felt stoned/groggy but kept waking up. A bit disappointing after my good sleep on the first night.

On the plus side, any vaginal irritation has totally cleared up so it was obviously being caused by the Utro.

I have a Newson appointment tomorrow so hopefully I’ll get some good advice!

Thanks again for your input too.
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Banjo1973

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Re: Sensitised to utro - running out of options
« Reply #20 on: November 22, 2023, 08:53:37 PM »

Please share what Newson say to you.

Thank you Hurdity for your input- I really value your wisdom but I am a desperate woman who is willing to try some unorthodox approaches.

My next step is requesting cyclogest. But first, I will see how my womb lining is doing after my scan next week.

Thanks again for your help
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Peri2022

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Re: Sensitised to utro - running out of options
« Reply #21 on: November 23, 2023, 02:58:44 PM »

Hi ladies, I’ve just had my Newson appt so I thought I’d pop in to update you if it’s helpful at all.

-Estradot: she says their pharmacy had good stock of all Estradot apart from 100mcg. This is great for me as I just need 50 which I can’t get locally.

-irritation from utro - she agrees that this may be caused by the beginnings of vaginal atrophy/thinning tissue which is now more sensitive to utrogestan than it was. She is starting me on vaginal estrogen pessaries.


-she says there’s no good evidence about the effectiveness of rectal utrogestan so she’d discourage that. But I could take cyclogest that way in the future if I decide to swap formulations.

-I asked about testosterone for energy/brain function. She was happy to start me on it but I prefer to get my bloods done first to see if I actually have low T levels, so she is arranging that for me, and then we’ll see.

All in all she was lovely and I was very satisfied that all my concerns were heard and addressed. It is expensive but as I say I got the NHS discount and being seen within 48h is virtually priceless!

Hope that helps x
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Banjo1973

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Re: Sensitised to utro - running out of options
« Reply #22 on: November 23, 2023, 05:34:59 PM »

Thanks for sharing - super useful information.

Hope the oestrogen pessaries help x
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sheila99

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Re: Sensitised to utro - running out of options
« Reply #23 on: November 23, 2023, 09:22:04 PM »

If you look at the ivf forums there's a bit more info about using utro rectally. It seems seems some places are happy this way but others aren't. I'm working on the theory that a decent bleed=OK, I'm not sure I'd use it conti this way without scans. So far for me it's been more effective than vaginally.
I think  utro gets in the bloodstream vaginally and rectally, I can't see how I'd fatigue and disturbed sleep if it didn't. I've stated taking it in the morning and hoping the effects have worn off by night.
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Banjo1973

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Re: Sensitised to utro - running out of options
« Reply #24 on: November 23, 2023, 10:00:05 PM »

Hi Sheila99,

Thanks for that. I too have seen IVF threads where some women have been advised to use it rectally in special circumstances.

I'm the same as you - I have to take it in the morning otherwise I don't sleep.

I'm going to continue to use the back route!! At least I'm not skipping it altogether.

I've got a scan on Monday, fingers crossed my lining is ok.

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sheila99

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Re: Sensitised to utro - running out of options
« Reply #25 on: November 24, 2023, 09:52:08 AM »

Good luck, I hope it's OK.
 It would be nice if Newson did some research on this, it doesn't look as though anyone else will.
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Banjo1973

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Re: Sensitised to utro - running out of options
« Reply #26 on: December 01, 2023, 08:04:01 AM »

Hi Sheila99

My scan came back clear. No thickening of the lining. I am very lucky.

I 100% agree with you that there does need to be some extensive research on this because many women like us are struggling with the progesterone element of HRT.

I think I will continue with the unorthodox route and maybe have yearly scans.

Thanks for your help.
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purplebee

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Re: Sensitised to utro - running out of options
« Reply #27 on: December 01, 2023, 11:57:06 AM »

I tried Utrogestan for a few weeks vaginally but had to stop due to itching and soreness.. I know it's not licensed in this country for vaginal use, although many women use it this way. I had to stop and go back to Evorel Conto because of it, it's a common complaint.
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sheila99

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Re: Sensitised to utro - running out of options
« Reply #28 on: December 01, 2023, 04:23:53 PM »

Oh that is good news Banjo  :). I'm on my 4th cycle rectally now so will see if I bleed again this month, I'm past the 6 days where I've bled previously. I'm still on 200mg.
Purplebee I don'thave that option as I'm on 100mcg oestrogen now and sadly they only make conti patches with 50. I had no side effects from evorel conti, for me it was better than utro.
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HaRuHaRu

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Re: Sensitised to utro - running out of options
« Reply #29 on: December 01, 2023, 07:26:03 PM »

Sorry I’ve not read all replies but just to say I couldn’t tolerate Utrogestan even vaginally for all sorts of reasons but it also made me very sore. I’m now using Cyclogest pessary which isn’t perfect but I tolerate it much better. It’s messier than Utrogestan as it’s cased in wax that melts and comes out so I feel it’s not a long term option but good enough for me for now while I figure out the other elements. Might be worth a try?
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