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Author Topic: Progesterone Intolerance  (Read 1932 times)

LisaBenno

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Progesterone Intolerance
« on: August 17, 2021, 08:15:45 PM »

****edit- I know it is a long post, but can anyone offer advice, also does anyone take utrogestan continually and get on okay with it please? *****

Hi,  I am looking for some advice please…

I am seven years post Op BSO, still have uterus.
In that time I have tried various types of HRT and haven’t had much success at all as I really struggle with progesterone, it makes me feel like I did when I had PMDD prior to surgery.

After years of unsuccessful GP visits, I ended up paying privately and was advised to try utrogestan 200mg vaginally days 15-28 along with Estrogel (2 pumps).
I managed just a few months on that regime and in that time experienced the usual horrible side effects of the progesterone (tearful, irritable, angry) plus heavy bleeding so unfortunately had to stop.

Some of the symptoms I had been experiencing, such as brain fog, hot flashes etc did ease with the HRT but the other side effects sadly outweighed these.

I went to see the gynaecologist a few days ago, as I had been referred to see if I could have a hysterectomy. She did say this was an option, however, she was concerned that a hysterectomy may be unnecessary surgery if I am simply not suited to HRT (which I understand)

She has asked me to think about the Mirena coil, I did explain that I had tried it once before and it didn’t agree with me so I had it removed when I was having my oopherectomy. She said it would be different now as I don’t have my own progesterone therefore shouldn’t feel the effects of it the same….I am not convinced to be honest.

Have any of you had a Mirena coil fitted post BSO and if so, how have you found it please? This really is my last option before further surgery so would really appreciate any advice please!

« Last Edit: August 18, 2021, 08:10:29 PM by LisaBenno »
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VictoryV

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Re: Progesterone Intolerance
« Reply #1 on: August 21, 2021, 01:37:50 AM »

Hi Lisa,
I don’t have the experience you’re looking for, am on my first try with HRT and am searching for answers like you. I’m looking through posts that are ten years old, there are so many!
I can hear worry in your post so I hope the answers for you are in the previous posts or someone posts with their experience.
If I find anything I think might help I’ll link it here.
I wouldn’t have a surgery without knowing all the facts but that’s just me.

Take care.
Victoria☀️X
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sheila99

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Re: Progesterone Intolerance
« Reply #2 on: August 21, 2021, 10:00:36 AM »

No experience either but there are other (limited) options. Provera suits some people who haven't been able to tolerate utro. The other option is to reduce the utro. You could use a long cycle (6 weeks). According to Louise Newson you can halve the dose if using it vaginally so 12 days x 100mg. Some people use as little as 7 days x 100mg. But this comes with a warning. On your dose of oestrogen you will probably be OK on 12 days x 100mg but if you use less than the standard dose it would be good to have a scan after a few months to make sure your lining remains thin. You may not get it on the nhs but you can arrange your own privately. Not sure what you'veaalready tried but could try a patch with a different form of progestogen (see treatments tab) as you may find you're OK with something different. Hopefully someone can answer your question about the mirena but if you were really bad with it I'd be a bit doubtful you will be OK now.
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