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[Gilla999]

I'm on two sprays of Lenzetto and it has generally worked wonders for me, however i am on slightly too high a dose and it's causing some issues for me. I tried cutting from two sprays to one spray after my period, but that was a nightmare - I literally had withdrawal similar to what I have if I reduce my antidepressants too quickly, I felt seriously ill (didn't have a return of my symptoms, just felt very, very ill). I'm guessing there isn't any way to reduce the dose more slowly, but just wondered if anyone had any suggestions?

I am considering switching to Oestrogel as it's easier to taper, but it just seems a shame when I've got on so well with Lenzetto!

[CLKD]

Why do you think that you are on too high a dose 

It may B that you choose to drop a dose at the 'wrong' time of the cycle? 

There isn't any advice on the 'Lenzetto' info. - I did a google. 

[Salad]

Just to clarify Gilla- the two sprays, is that one spray twice a day or two sprays together?

If it’s two together then the first thing I’d try is to split it one morning and one 12 hours later. X

[Gilla999]

Although my original symptoms (night sweats and horrendous insomnia) have disappeared since starting Lenzetto, I put on a stone in the space of two weeks (!!) have horrendous and persistent constipation, painful boobs and abnormally high cortisol (all of which are symptoms of too much estrogen). Also just before ovulation I am feeling completely manic and hyper and then having a couple of days where I don't sleep until ovulation has passed, a pattern which is very out of the ordinary for me.

I feel like my estrogen is just a little bit too high and would like to try to lower just a bit and see how I get on with it. CLKD I also wondered if I dropped at the wrong time in my cycle - I am massively sensitive to stuff like that! Perhaps I'll try dropping in the second half of my cycle when my own estrogen is still rising, rather than at the very start when it's already at its lowest.

Salad by two sprays I meant two sprays at once in the morning. The thing is separating them will be still cause me to have the same level of circulating estrogen... I just want to find a way to try 1.5 sprays (which is 3 pumps of oestrogel) but it does seem a bit impossible on Lenzetto! Thanks ladies for your replies xx

[CLKD]

MayB put 'lenzetto' in2 the search box 2 C if any threads pop up?  Make notes 

It's difficult to get a balance sometimes, it's Trial and Error which can be so tiring 

[Gilla999]

So true! And every change you have to really give a cycle. I also considered whether taking Utro orally (instead of vaginally) might help balance the estrogen out but the next-day tiredness from taking it orally is overwhelming for me... I don't know how other ladies do it!!

[SueLW]

Take 1 spray every day and 1 spray every other day. That’s effectively dropping the dose by half a spray.

For me Lenzetto is the best of all oestrogens. It’s great. But fine tuning is harder.

[Gilla999]

Totally agree on the Lenzetto Sue! I wondered if I did the alternative days whether that would mean I was getting an erratic dose of estrogen and could cause problems? I'm not sure if it's that "reactive" or not per day.

I have for now decided to take up half of my Lenzetto with parcel tape and see how that works 

[Shannonplussed]

I don’t have any tips about the spray,  but I wanted to say I feel much the same when I feel like my estrogen is getting too high. I lose a little weight and poop so much better when I decrease the dosage, even temporarily. I feel as though the estrogen builds up in me and I’m feeling the need for breaks for fine tuning. But I know I do need some amount. Tricky to walk that line (but still so much better than it once was—fine tuning is a good place to be!).

[Gilla999]

Thank you Shannon, that's actually really helpful to know as I'm still new to all of this and going on my own gut feeling. And as you say there has been a whole world of improvement since this time last year, so I'm very grateful just to be fine tuning now.

My sense is that when I tried to halve my dose and drop to 1 spray of Lenzetto last month it wasn't the dose itself that was too low per se, it was more the withdrawal from the high amount of estrogen I've been pumping my system with over the last 7 or 8 months (prior to starting Lenzetto I had tried the contraceptive Pill and did 5 packs back-to-back). I am super sensitive to stuff so it's not a huge surprise (I felt really, very ill!)

On the digestion - I've noticed that when my period arrives it gets temporarily better for a few days and it's such a relief - this coincides with the time when my own estrogen naturally drops, so I'm certain the estrogen is to blame (it's also a known side effect of estrogen).

I'm going to give taping the spray up a go and hope I can wean myself down a bit more gradually. Thanks all for your help, much appreciated 

[Pippa52]

Hi Gilla999
I have just switched to Lenzetto after being on Oestrogel for over 20 years. I was told to start at one spray then after a week increase it to two.  Two sprays were way too high for me I was almost on the ceiling so I have taped off 2/3rds of the Lenzetto opening and am  on one spay plus 1/3rd of a spray.  I feel I am starting to level out on that as having worked out the equivalent dose I was on when taking Oestrogel this seems to be the best way to replicate it.  I have 2 applicators of Lenzetto on the go - one for the full spray and the other one is the taped off one which delivers 1/3rd of a spray.  Hope that helps xxx

[Gilla999]

Thanks so much Pippa, Scampi told me this idea of yours and it's working a treat! I have two sprays on the go as well, with one being a third taped off. Today is day 4 and so far so good, but I know last time when I tried to reduce from 2 to 1 sprays that it didn't hit me until about 7-10 days in. Really hoping I get on ok with this. Thanks for coming up with the genius idea 

[Pippa52]

Gilla999

Oh that's brilliant I am so glad it was helpful and so far appears to be working well.  I thought I might write to the manufacturer about this actually as I am sure we are not alone in needing to be able to taper the dose to suit us. Maybe another extra lid could be put in the pack that could be adjusted somehow for those of us who need to have some smaller doses.  I am sure it's possible.  Fingers crossed it goes on working for you.  I am beginning to feel loads better on the slightly lower dose too. Yay xxx

[Gilla999]

I agree, I read a lot of people who like me are fans of Lenzetto, but the one drawback for me is the inability to taper your doses (or even just have a smaller dose like you can with a 25mcg patch for example).

Can I ask how long it took you to start feeling a bit better Pippa? Do you plan to stick on the dose you're on now?

[Pippa52]

Hi Gilla999

Yes I do plan to stick to the dose I am for now (1 full spray and  1/3 rd of one spray) until I am reviewed by the Consultant in October.  She did prescribe 2 sprays but that literally had me on the ceiling with headaches, anxiety and feeling really twitchy and hot.  This dose seems, so far to suit me better.  I am still getting some hot flushes but much less so...I am definitely sleeping better too at long last.   I have been on Lenzetto for 18 days now and so much prefer it to Oestrogel.  It seemed to kick in very quickly as I was expecting several weeks to stabilise but I am definitely starting to feel much more level now already.  It may be that in the future I might need to increase it but I am due to have another oestrogen level blood test done one week before my review so it will be very interesting to see what the levels are now.  So hope you are starting to feel better too xxx