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[Pippa52]

Hi Everyone
I am due to change from Oestrogel to Lenzetto this week.  Is there anyone else taking Lenzetto which I gather is quite new over here in the UK? If so how are you getting on with it?  Many thanks in advance for any info - am very nervous about changing over as new medications always give me side effects to start with. xx

[Salad]

Hey Pippa52

I am using Lenzetto 
It’s in addition to my patches as my Oestrogen levels wouldn’t come up. I’m getting on really well with it. I became a Grandma in March as I was starting the spray and the information leaflet seems to say keep babies/children away from application site. So I’m using the underside of the top of my arm instead of the forearm as suggested. I use two sprays in the morning and one at night.

Hope you get on ok - let us know how it goes x

[Gilla999]

I've been using Lenzetto for just over 3 months now and I love it. It's so easy to use (I couldn't get on with Estradot) and I have only positive things to say about it - it has literally been a life-saver. xx

[Pippa52]

Thanks so much for the replies.  It's so good to know that others are having such success with Lenzetto.  I started using it yesterday and so far so good.  I seem to be feeling a lot more level already which seems rather a quick response but I was on quite a high dose of Oestrogel so not starting from scratch.  I have been advised to start on one spray and then the Dr will re-assess now that my blood oestradiol results from when I was on Oestrogel have come back as to whether I need to put the dose up to 2 sprays.  As you have both rightly said Lenzetto is so easy to use - anyway so far so good and thanks so much for the positive replies. xx

[DottyP]

Thanks so much for the replies.  It's so good to know that others are having such success with Lenzetto.  I started using it yesterday and so far so good.  I seem to be feeling a lot more level already which seems rather a quick response but I was on quite a high dose of Oestrogel so not starting from scratch.  I have been advised to start on one spray and then the Dr will re-assess now that my blood oestradiol results from when I was on Oestrogel have come back as to whether I need to put the dose up to 2 sprays.  As you have both rightly said Lenzetto is so easy to use - anyway so far so good and thanks so much for the positive replies. xx

Hi I just wondered how you got on with Lenzetto?   I was on Oestrodose at one pump which was working wonders (had been on it for two months) then had to change to Oestrogel which brought symptoms back and was taking 20 mins to dry so my GP suggested Lenzetto.  I’ve been on that for a week at one pump - which she said was equal to one pump of gel - but I’m getting symptoms again like dizziness, lethargy and the awful itchy skin and straw like hair.  So gutted because all of this had gone with Oestrodose.  My GP isn’t very clued up on Menopause and whilst I’m on at least two private meno waiting lists there isn’t an NHS clinic near me.  SHould I up my dose to two sprays?  Could it be that I’ve just started the Utrogestan part of the cycle so that may be why I’m getting more symptoms?  So confusing.  REally don’t think I agree with Utrogestan.  I’m only taking 100mg orally for 12 days as I know my body couldn’t handle 200mg.  Any help would be appreciated.  Thank you. 

[Suza]

Hi
I started on lenzetto about 2 weeks ago having previously had a 6 month break from hrt then 4 months on evorel 25 patches
I was advised to start on 2 pumps daily which I did, but found that as I've described in a previous post, my nipples were getting incredibly sore, so I dropped down to 1 spray daily a few days ago and the pain seems to be going
Apart from that symptom I'm finding it really easy to use and keeping the dreaded flushes and night sweats at bay

[Brindle]

I recently changed to Lenzetto after using Estrogel. The gel took so long to dry I wanted to try the spray. Just after starting this my breasts, especially the nipple area became really sore, constant nausea, and stomach cramps started. I thought initially I had a bug but then wondered if it was the spray. I've decided to take a short break to see if that is the case. Has anyone else had similar reactions? Also had very itchy skin.

[Evangelista]

I use Lenzetto and was prescribed one spray but upped it to two, partly on the basis of symptoms and partly because of a question mark over the actual amount of oestrogen delivered in each spray.
Dr Louise Newson has been on correspondence with the manufacturers and they've said it's only half as potent as described.  They are updating the info leaflet to reflect this.
Tender breasts and itchy skin are signs of an oestrogen issue, and it seems they can be caused by too high or too low levels.....!!
Given the issue over the strength of the Lenzetto dose I'd say you should increase by one spray and see what happens.
I changed my dose without consulting my GP but wouldn't necessarily suggest that's the sensible option for everyone. 

[Brindle]

Thanks for that. My doctor did look up the dosage and noted that it was weaker than the Oestrogel, so advised 2 sprays initially to be upped to 3 if needed. She also said that she had recently been on some training and that they now recommend the best place to put sprays or gels is in the small of your back.

[Postmeno3]

I'm about to start Lenzetto spray and worry if it is weaker what its efficacy can be for poor absorbers.

[Evangelista]

Thanks for that. My doctor did look up the dosage and noted that it was weaker than the Oestrogel, so advised 2 sprays initially to be upped to 3 if needed. She also said that she had recently been on some training and that they now recommend the best place to put sprays or gels is in the small of your back.

Interesting... I wonder how they think you can hold the spray device in place in the small of your back.....! Contortionist is not on my skills list!

[Brindle]

I thought that initially, but it is easier than you think . The GP calculated that 1 and a half sprays of Lenzetto is equal to one of Oestrogel.

[Evangelista]

Just wondering whether you'd get the same 'suction' on the lower back. Plus sometimes there's more liquid and it runs so I hold my arm horizontally once I've sprayed. Imagine where it runs from your lower back, lol.

[DottyP]

I thought that initially, but it is easier than you think . The GP calculated that 1 and a half sprays of Lenzetto is equal to one of Oestrogel.

The specialist I spoke to today said they are thinking that one spray can be as low as half a pump of gel so told me to up my one spray to two.  I’m hoping this works but now worried that two sprays will be too much - I was on one pump of gel before.  It seems no one actually knows what the dosage is, including the manufacturers - I read somewhere that they said you don’t necessarily get the same amount each spray or it affects differently women differently!  It’s a nightmare minefield and feels a little as if we are guineapigs

[Evangelista]

I did actually manage to use the spray on my lower back today,  after a bit of twisting in front of the mirror.

As to the dose, the manufacturers are meant to be updating the leaflet,  but by the sounds of it, even they don't know what it is!

The leaflet suggests that you get the same dose per spray,  but I don't see how that can be because some sprays provide enough liquid that it runs, and some don't.

Fortunately I don't seem too sensitive to the variation,  but I imagine it is hard if you are sensitive to it.