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Author Topic: Evorel patches and bleeding  (Read 10951 times)

florriepeck

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Evorel patches and bleeding
« on: April 21, 2021, 03:26:44 PM »

I'm currently on Evorel 75 patches and utrogestan 2 capsules every day: my menopause specialist GP changed me to this 6 weeks ago from Evorel 100 patch and utrogestan i capsule daily, due to recurrent bleeding.
Bloods showed oestradiol levels to be lower than GP would like ( this was after 4 weeks of 75 patch).
I'm waiting for a pelvic ultrasound.
Still bleeding intermittently: not heavily, more of a brown discharge, but so inconvenient, and with the aching legs/ joints of a proper period.
I have to contact my GP in another month to let her know how I'm getting on.
Anyone else had this unpredictable bleeding?
I only have a week or so bleed-free, then it starts up again.
I'm 57. I started originally on 50 strength patches, and wasn't bleeding on them, but vasomotor symptoms were not controlled.
Would appreciate any advice.
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Taz2

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Re: Evorel patches and bleeding
« Reply #1 on: April 21, 2021, 10:45:07 PM »

Bleeding is not considered abnormal for the first six months of a continuous HRT regime. How lon in total have you been on a conti HRT?

Taz x
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florriepeck

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Re: Evorel patches and bleeding
« Reply #2 on: April 23, 2021, 09:04:33 PM »

First started 11 months ago
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Hurdity

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Re: Evorel patches and bleeding
« Reply #3 on: April 24, 2021, 04:46:33 PM »

It sounds like a classic case of the progesterone dose ( especially if only 100 mg taken orally) being insufficient to protect the uterus from a higher dose of oestrogen - in your case 100 mcg patch. Docs don't normally test oestrogen levels and should go by symptoms although private menopause docs always seem to ( and charge for them!).Interesting that it was your GP who talked about your oestrogen levels.

At your age unless they are very low and you are taking HRT for oesteoporosis then actual oestrogen levels are irrelevant as long as the dose is controlling your symptoms. In your case it wasn't hence the incrrease - but 100 mcg is a big jump from 50 mcg!

Good that you are having a scan to check the thickness of your womb lining and then you will be able to take it from there depending on the outcome eg you could maybe have fibroids or something else causing the bleeding maybe?

There is a possibility that the bleeding is from a natural ovulation but less likely at your age and also depends on what your (natural) periods were doing before you started HRT?

Let us know how you get on!

Hurdity x
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sheila99

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Re: Evorel patches and bleeding
« Reply #4 on: April 24, 2021, 08:58:48 PM »

If you had bleeds before hrt and it feels like a period I think it's likely it is. Some women are in their early 60s before the reach meno and a late meno seems to be more common that doctors think. Despite being told by a meno specialist everyone was meno at 54 I still had pretty regular periods before going on hrt at 57. If you weren't meno before you went on hrt you might be better with a sequi regime.
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florriepeck

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Re: Evorel patches and bleeding
« Reply #5 on: May 09, 2021, 10:42:13 AM »

So, my NHS letter appointment came through quickly, and I'm going for a pelvic ultrasound scan this week ( and it says in the letter probably a transvaginal scan, too?).
I'm still bleeding on more days than not, still continuing on Evorel 75 patch and 200mg utrogestan.
I'm going to e mail my menopause dr ( Newson) after my scan and let her know how I'm getting on.
I don't know if I'll be given any information at the scan appointment re endometrial thickness, so that I'll be able to tell menopause dr in my e mail.
Hopefully, womb lining will be okay, but then I don't know what the next HRT step could be.
I didn't have much bleeding when I first started on Evorel 50 patches, but symptoms weren't quite controlled.
I know that people have worse problems to deal with, but the persistent bleeding is really getting me down.
Anyone know what could be considered as more suitable HRT?
I'd like to be thinking ahead of what Newson dr might suggest, so that I can read up on it.
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sheila99

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Re: Evorel patches and bleeding
« Reply #6 on: May 13, 2021, 08:33:27 AM »

The scan may give you the answer to the bleeding. Do ask any questions when you're there, they told me how thick my lining was but only when I asked. If they don't find anything to explain the bleeding you might consider a mirena which will usually stop it. 
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florriepeck

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Re: Evorel patches and bleeding
« Reply #7 on: May 13, 2021, 08:51:45 PM »

So I’ve been for the scans and my womb lining is 5.3mm.
Newson dr has said that it being over 5mm means that I may need a hysteroscopy.
I’m speaking to her tomorrow about her suggestion of changing my utrogestan to provera 5mg daily short term to control this bleeding.
Does anyone have experience of a situation like this?
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Stockport1965

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Re: Evorel patches and bleeding
« Reply #8 on: May 14, 2021, 07:06:04 AM »



At your age unless they are very low and you are taking HRT for oesteoporosis then actual oestrogen levels are irrelevant as long as the dose is controlling your symptoms.
Hurdity x

I use mine for Osteoporosis, do you know what strength I should be on or where I can find the info. Thanks
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SAX74

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Re: Evorel patches and bleeding
« Reply #9 on: May 14, 2021, 08:02:01 AM »

I had continuous bleeding for over 12 months and had the pelvic ultrasound and hysteroscopy which showed everything was normal. I was advised to have a mirena coil when I had the hysteroscopy and it was the best thing I ever did. The heavy bleeding stopped  within a few days and I just had an Evorel 50 patch for the oestrogen. I hope you get sorted soon x
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Joaniepat

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Re: Evorel patches and bleeding
« Reply #10 on: May 14, 2021, 09:05:24 AM »



At your age unless they are very low and you are taking HRT for oesteoporosis then actual oestrogen levels are irrelevant as long as the dose is controlling your symptoms.
Hurdity x

I use mine for Osteoporosis, do you know what strength I should be on or where I can find the info. Thanks
Your serum estradiol level needs to be at least 350pmol/l for bone protection. The strength of the product is irrelevant as women absorb oestrogen differently from different products, so you need a blood test to find out if you are achieving the right level.
JP x
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Stockport1965

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Re: Evorel patches and bleeding
« Reply #11 on: May 14, 2021, 09:07:47 AM »


GP won't do this test


At your age unless they are very low and you are taking HRT for oesteoporosis then actual oestrogen levels are irrelevant as long as the dose is controlling your symptoms.
Hurdity x

I use mine for Osteoporosis, do you know what strength I should be on or where I can find the info. Thanks
Your serum estradiol level needs to be at least 350pmol/l for bone protection. The strength of the product is irrelevant as women absorb oestrogen differently from different products, so you need a blood test to find out if you are achieving the right level.
JP x
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florriepeck

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Re: Evorel patches and bleeding
« Reply #12 on: May 14, 2021, 02:19:55 PM »

Update, I'm to continue on Evorel 75 patches and utrogestan 200mg daily for now, and GP has referred me for a hysteroscopy, and said that I should hear from local hospital within a week.
She advised me to request sedation for the procedure.
I've been reading on NHS website that it can be done under a GA if you prefer: which I think I would!
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SAX74

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Re: Evorel patches and bleeding
« Reply #13 on: May 14, 2021, 02:49:06 PM »

I had my hysteroscopy done under GA and had no problems at all. Good luck!
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florriepeck

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Re: Evorel patches and bleeding
« Reply #14 on: May 14, 2021, 03:19:18 PM »

That’s reassuring: did you have to ask for the GA?
I’ve been reading some horrendous accounts of women having the procedure without, and I think I’d be tempted to not have it done if that was the case.
Maybe it depends on area or dr: I’ll wait for my letter I suppose.
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