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[Tc]

Hurdity thank you so much for your reassurance and advice.   

I  had thought I was o.k on the 3 months I used femseven 50 (well remembered) but  I cant be 100% sure as it was my first try at HRT and I didnt know enough then to figure which  hormone might be causing which side effects. . But As you say its early days with the mirena and (touch wood) I'm not getting worse and worse depression wise yet which I did on utrogestan. So if it stays like that it's a huge improvement. Maybe for the moment I need to take mirena  out the picture and give it more time.  Clarifying the implant situation is a priority.

After another bad night . I realy now think its low E symptoms.   The implant should have kicked in by now and it can fail. KBs did.  I believe that is a  more easily solvable  scenario, of the two and I would be happy to go back on sandrena as  I know I absorb it.   

But tachyphylaxis  presents as the very same  low e symptoms too. And it's a lot more of a concerning scenario.  But don't worry hurdity, you didnt scare me by mentioning it I already knew about it as it is mentioned on c and w website. .

Thanks for the advice on bloods. . Once I get results I can contact the clinic.  If my E is low It may be that they tell me to lower Tedtogel  i guess until its sorted.   Tbh I dont think I would miss it at all it seems to have no benefits for me after nearly a year. .

Thanks again. Much appreciated. I will report back on my results.

Xxxx

[Tc]

Update.

E has tested at 266pmol.  So it's a drop from what I was getting on the sandrena.( 358)  Quite a big drop  realy proportionately.

So Very disappointing.  And a bit confusing.  I assume it hasnt failed completely as with no ovaries my E would be lower than that surely?. but its still lower than the implant is supposed to give (300 to 600) which I dont think anyone certainly not my gynae expected.

Xxx

[Alicess]

Hi Tc,

Do you know what your SHBG is? Do you feel a bit better despite lower E?

Alicess X

[Mary G]

Tc, I can't remember how old you are but broadly speaking 300-400 pmol is the ideal level for post menopause women on a maintenence dose of HRT for symptom relief and bone protection etc.

My oestrogen levels are always between 270 and 300 pmol and I don't have any symptoms but I am 58 now very post menopause.   Ten years ago that level would not have been anything like enough so it depends on your particular needs and what stage you are at.

Can you top it up until the implant is due to be renewed?   Perhaps you can have a higher dose implant after that.

[Hurdity]

Update.

E has tested at 266pmol.  So it's a drop from what I was getting on the sandrena.( 358)  Quite a big drop  realy proportionately.

So Very disappointing.  And a bit confusing.  I assume it hasnt failed completely as with no ovaries my E would be lower than that surely?. but its still lower than the implant is supposed to give (300 to 600) which I dont think anyone certainly not my gynae expected.

Xxx

Hi tc - levels per se above a certain level for bone protection ( which is much lower) are not important (unless too high) but of course symptoms are, so if your symptoms have returned since the implant compared with the Sandrena then that is disappointing. I don't know what the stabilisation period for pellets is as they are unlicensed so the product info is not available on EMC unless you know the brand name and I can look it up?

Don't forget the Sandrena levels will vary according to time since gel application and to some extent where the blood was taken relative to where you applied the gel. I presume you could be offered a top-up if necessary like you did when you first had the implant?

Absolutely - you would have nowhere this level without the implant. Post-menopausal levels are variable for different women but low. I wold be very happy with an estradiol level like this - but like I said it is your symptoms which are indicative.

Hurdity x

[Tc]

Alice's. SHBG and T not back yet.

Mary g . I'm 55 but I was still reg periods at 53 when I had ovary removal so in  a way  it wasnt a slow decline being eased or balanced by HRT it was a,sudden drop . So I guess my body has to get used to going from early peri to post overnight and atop craving the previous level and  learn to live on lower amounts.without such severe symptoms. I'm hoping with time that will happen as it would have naturally in my mid late 50s.

Hurdity. My low e symptoms are all still there.  Flushes returned compared to sandrena too.

  But. There is some good news. Finally. !!!

I havent wanted to speak too soon but .depression and even anxiety have eased for the first time in 18 months. which is a biggie. Its huge actually.  It has  made so much difference to me. It's not down to any outside factors or changes in my life.  Given as I always thought it was hormonal then maybe it's down to  the consistency of dosing the implant gives compared to gel and the mirena does the same.  Maybe less fluctuation was the key to that. In which case it's an advantage of my new regime over the gel.and utro.  But it's just obviously not high enough to combat the other symptoms. 

 I dont know the name of the implant just that it was 50.
I could try topping up with sandrena.  Just a bit at first and see if it helps flushes etc.  Its a plan.

Thank you all stay safe. Xxxx

[Joaniepat]

So glad to hear this Tc. I'm sure you're right about the consistency of dosage. Let us know how you get on with the Sandrena top up.

JP x

[Tc]

Thanks jp I will do.  X

[Countrygirl]

That sounds really promising Tc, I'm so pleased to read this x

[Alicess]

Please to hear this too., Tc. Maybe topping it up with Sandrena will get rid off other symptoms too. Take care Xx

[Mary G]

Tc, great news the reduction in depression and anxiety, this is very likely to be because of the hormone stability.

How are your migraines?  If you have noticed a reduction in them, I think you are on to a winner with your new regime.   

I've been reading up on oestrogen implants and they like the most stable delivery system for oestrogen and testosterone.

[Tc]

Thank you ladies.
Mary I have had headaches but I havent had a bad migraine (the sick ones I call a "bonzer)  for a few weeks   

I was due to get the testosterone one in may but not sure what will happen with that now.  But just to be feeling better mentally is huge. 

Xx

[bear]

Hi Tc,

So happy for you, we do need good news 

BeaR.

[Tc]

Thanks beaR xxx

[Mary G]

Tc, the fact that your migraines have subsided would suggest you have achieved hormone stability which is great.   As you probably know, migraines and mood are closely linked.

Fluctuating hormones are bad news for migraine sufferers and according to my migraine specialist, migraines with aura are caused by oestrogen spikes (sometimes referred to as oestrogen dominance) and migraines without aura (often the painful, sickly variety) are caused by sudden drops in oestrogen.  Obviously hormone stability is a must for both types of migraine.

The headaches could be a sign of low (low for you that is) oestrogen levels so it might be worth topping up if you can and see if the headaches and other symptoms subside.

Like BeaR says, it's so nice to hear some good news for a change!