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Author Topic: Is this the right place to discuss compounded hormones?  (Read 111617 times)

Marchlove

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Re: Is this the right place to discuss compounded hormones?
« Reply #465 on: March 30, 2022, 03:39:06 PM »

Ah yes VictoriaV, you certainly can with mine! That might work CrispyChick? x
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VictoryV

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Re: Is this the right place to discuss compounded hormones?
« Reply #466 on: March 30, 2022, 04:02:13 PM »

I’ve never seen a lozenge, is it solid or soft centred?
How big are they, can one be cut up equally without precision tools?
I’m assuming they come in different doses, is a lower dose pill smaller in size or the same size as a bigger dose?

Sorry for the Q’s, I’m interested!
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CrispyChick

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Re: Is this the right place to discuss compounded hormones?
« Reply #467 on: March 30, 2022, 04:08:02 PM »

Yes. It's a square. Suspect it'll get less accurate the smaller I cut.

I think they are all the same size (irrespective of overall dose e.g a full troche can be 100mg or 200mg or contain other hormones too. Mine are 100mg) and can easily be quartered. Smaller than quarters probably not so precise. But it does cut.

The pharmacist suggested I try an 1/8 instead of my 1/4 in morn.

I think I might try 1/4 and 1/8 tonight as I sleep through anything - leaving 1/8th tomorrow to take. Perhaps the headachy feeling will come to nothing if I just take at night... More trials. Sigh. Time will tell.

Feeling dispondent... But I guess I'm on the dip come down for the day  ;D

Thanks ladies  :-*

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Marchlove

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Re: Is this the right place to discuss compounded hormones?
« Reply #468 on: March 30, 2022, 04:25:48 PM »

Mine is round with softish centre. Easily cut into quarters x
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CrispyChick

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Re: Is this the right place to discuss compounded hormones?
« Reply #469 on: March 30, 2022, 04:28:54 PM »

 :o how funny they are different. Mine is same consistency all the way through... Like wax.
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Marchlove

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Re: Is this the right place to discuss compounded hormones?
« Reply #470 on: March 30, 2022, 04:38:34 PM »

Yes sorry, mine is like wax, so easy to cut
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VictoryV

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Re: Is this the right place to discuss compounded hormones?
« Reply #471 on: March 30, 2022, 05:27:51 PM »

Thanks CrispyChick.

It sounds like you feel your hormones quickly increase (woozy, sicky) and then drop off (irritable, low) 4 hours later. I don’t know what daily dose you’re on but if you can divide the troche into 6 or 8 and space it throughout your day you might avoid the see-saw effect you’re getting? I don’t think it matters if the pieces are not absolutely identical, the key is getting the pieces small and timing regular/frequent.

Marchlove - you’ve mentioned mouth ulcers. Is your lozenge/troche PEG based?

I’m a long way behind you on this progesterone journey, hopefully one day I’ll have something useful to post!
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Marchlove

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Re: Is this the right place to discuss compounded hormones?
« Reply #472 on: March 30, 2022, 05:45:53 PM »

Yes it is VictoriaV!!!
Good thinking. I wonder if the sublingual drops are too? MaryG would know.
I also take estrogen lozenge and have no problem with those, they don’t have PEG. I thought the difference might me that estrogen is very good for your mouth and gums, but that could be the reason.
So golly you might not be as far behind us as you think, so post away!
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CrispyChick

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Re: Is this the right place to discuss compounded hormones?
« Reply #473 on: March 30, 2022, 05:51:42 PM »

Exactly that Victoria. Although at the end of all that swinging up and down... I'm now back to my normal meh self with full ears and vagueness (hard to explain).

I will try my usual 1/4 tonight, plus an additional 1/8th...then chop my remaining 1/8 into tiny pieces tomorrow. My worry is I'll then be continuously woozy which i was on the cream.

I might hold off on the morn dose... See what happens... 🤔

Most woman take one hit a day with utrogestan though... So hopefully that might be an option.

Where are u at with your prog Victoria?

PEG is off putting, I must say. However, priorities at this moment in time. I had mild mouth discomfort the few days... But that seems fine now (a lot the only thing that is  ::)).

Marchlove - my pharmacist mentioned rapid melt wafers or something along those lines... Worth looking at. But then, if it works for you swallowing it... Stick with that 🤷‍♀️ although you'd prob be better on a  proper pill so you don't need to take the PEG in.
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Marchlove

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Re: Is this the right place to discuss compounded hormones?
« Reply #474 on: March 30, 2022, 06:03:50 PM »

Thanks CrispyChick. Is that the Specialist Pharmacy?
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VictoryV

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Re: Is this the right place to discuss compounded hormones?
« Reply #475 on: March 30, 2022, 06:05:00 PM »

I wish I had progesterone experience/knowledge! We spend 12 years doing algebra and get told diddly squat about this fantastic era 50% of us are signed up for!
PEG can cause nasty effects, maybe the compounding clinics offer a gelatin, VG, Vit E alternative. Does your estrogen lozenge name the carrier plz?

I’ll be gob smacked if sublingual drops contain PEG!
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Marchlove

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Re: Is this the right place to discuss compounded hormones?
« Reply #476 on: March 30, 2022, 08:03:51 PM »

Oh I’m an idiot  :'(, the estrogen does contain PEG!  I’ve just had another look with my glasses on and it does.

Feel a bit of an idiot, but thank you for raising this issue. 

So, I think it must be that the delivery system for me, not necessarily anyone else, is not the right one.

I’m grateful for your intervention though as it’s clarified for me that the sublingual route for me is one not to be revisited. x
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CrispyChick

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Re: Is this the right place to discuss compounded hormones?
« Reply #477 on: March 31, 2022, 08:27:41 AM »

Yes, specialist pharmacy Marchlove.

I see you've decided it's the prog not the PEG at fault though... So might not want to try an alternative sublingual.

I'm still pondering. Last night I took my usual 1/4 and an additional 1/8th. I was well aware of it... Went very woozy and felt wooziness if I woke in the night. This morning I felt sick as a dog.

Basically any dose of troche sends me woozy/spacey and aggitated. So it's not an option during the day with this side affect. After the slightly higher dose last night, I'll try no daytime dose. The fear is withdrawal headache... But can only test it.

Next stop will be oral. I have some 25mg capsules from my first 10 day trial. I'm wondering about a 50mg trial per night. The 25mg annoyed my estrogen symptoms, so wasn't sufficient. As I understand it oral absorption will be a lot less than sublingual. The pharmacist mentioned slow release capsules too... And I know you can take some capsules vaginally. So more trials to come.

The pharmacist said try for 2 weeks then go back to her... Basically, I don't heed to wait months each time as I'm only tampering with dose and route... Its not a whole new hormone.

It is frustrating to finally identify a need for progesterone and then struggle to take it due to side affects. 🙄

Anyone know if utrogestan is slow release???
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Perinowpost

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Re: Is this the right place to discuss compounded hormones?
« Reply #478 on: March 31, 2022, 09:04:17 AM »

I don’t know if utrogestan is slow release (hopefully others can help). However, I have some slow release 50mg progesterone capsules I bought privately, and I can tell you the side effects are no different to taking any other form of prog, i.e., low mood, spacey, sluggish, bloating etc. The only difference is it might take slightly longer to build up (as it’s a lower dose) than other progs, but it’s negative nonetheless. Sorry it’s not better news x
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CrispyChick

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Re: Is this the right place to discuss compounded hormones?
« Reply #479 on: March 31, 2022, 09:09:58 AM »

No, that's helpful perinowpost.

I am certainly feeling the build up as this week of troche has gone on... So I'm thinking I'll lower the dose to try and reach  lower side affects. I'm pretty sure the progesterone is helping balance my estrogenic symptoms... But the side affects... Urgh.
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