Mrs Bennett, Sounds very similar experience to mine. I went on vagifem for dryness a few months ago, no other bad VA symptoms. After a couple of weeks I got that constant wanting to pee feeling and then the most horrendus burning. It was pure agony, felt like I'd been sprayed with acid. The nurse swapped me to estriol cream and now I'm ok again, though do sometimes feel slightly uncomfortable. Like you, I find it really messy and its a bit of a faff, but worth it to stop the discomfort. My GP said that some ladies are able to go back to vagifem once they have symptom control from the cream, but I'm guessing that some people (maybe you and me) react to the fillers in it.