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[EleanorB]

Hi,

I was on three quarters of a patch of evorel 50 (oestrogen only ) for about 6 months. Due to a sudden dip into depression reminiscent of low mood prior to hrt I went up to a whole patch, with approval of gynae, about 3 weeks ago. The oestrogen has been unopposed with progesterone due to chronic migraine. I am suddenly having more palpitations, (had 24 hr halter a month ago nothing sinister)  abdominal pain/indigestion, bloating, fatigue, nausea, grumpiness (although depression has gone) I wonder if these are now hrt side effects as my dose is too high?

I am having a polyp removed from my endometrium in a couple of weeks and a mirena put in. I am stressed about this so could be that but it seems a bit OTT to be completely attributable to anxiety.

Has anyone had problems with an oestrogen dose too high for them to tolerate? I am thinking of going down to 3 quarters again as the depression, retrospectively, may simply have been news of the impending operation and dealing with uti issues.

Any thoughts welcome.

[Hurdity]

Hi EleanorB

Depends where you are in menopause but there is barely any difference between 3/4 patch and a whole patch when it's only 50 mcg to start with. Having said that I increased my dose to 62.5 from 50 mcg - not sure if i notice the difference though - but mine was to do with tesosterone and not wanting to become T dominant. Really 50 mcg is not a high dose at all so I would go with it if you can. Certainly grumpiness is more likely to be a side effect of low oestrogen or to do with progestogen. Oestrogen is the feel good hormone! Also does not cause fatigue - quite the opposite! Your symptoms could have nothing to do with hormones - and if they persist for some time do mention to your doc.

Are you post-menopausal? If so then could it be that your endometrium is building up and the cramps are heralding an (abnormal) bleed?  Once you have had the Mirena fitted you may well want to make sure your oestrogen levels are sufficient to counter the progestogen.

Sorry not to be of more help but good luck with the op and Mirena fitting and hope your symptoms subside.

Hurdity x

[Tracey E]

Hi Eleanor, if I take too much Estrogen I get terrible palpitations  Currently trying to find the correct dosage to improve my hot flushes without causing the return of the dreaded palps. It can be as finite as cutting a patch into quarters.

[bear]

Hi EleanorB

Depends where you are in menopause but there is barely any difference between 3/4 patch and a whole patch when it's only 50 mcg to start with. Having said that I increased my dose to 62.5 from 50 mcg - not sure if i notice the difference though - but mine was to do with tesosterone and not wanting to become T dominant. Really 50 mcg is not a high dose at all so I would go with it if you can. Certainly grumpiness is more likely to be a side effect of low oestrogen or to do with progestogen. Oestrogen is the feel good hormone! Also does not cause fatigue - quite the opposite! Your symptoms could have nothing to do with hormones - and if they persist for some time do mention to your doc.

Are you post-menopausal? If so then could it be that your endometrium is building up and the cramps are heralding an (abnormal) bleed?  Once you have had the Mirena fitted you may well want to make sure your oestrogen levels are sufficient to counter the progestogen.

Sorry not to be of more help but good luck with the op and Mirena fitting and hope your symptoms subside.

Hurdity x

Hi Hurdity,

What is testosterone dominance?

BeaR.

[bear]

Hi Eleanor, if I take too much Estrogen I get terrible palpitations  Currently trying to find the correct dosage to improve my hot flushes without causing the return of the dreaded palps. It can be as finite as cutting a patch into quarters.

Hi Tracey E,

I had the same on Estradot patches. I thought it was my asthma inhaler causing the palpitations, but as soon as I stopped HRT, they decreased. I still have them now and then, and this coincides with increased libido and other symptoms related to oestrogen surges.

BeaR.

[Sammiejane]

Hi Tracey e

How are you finding the estradot 75 patch ?

Hi Elenor b

I had same on everol patch but also had an issue with them sticking to

[Hurdity]

Hi Hurdity,

What is testosterone dominance?

BeaR.

Hi bear - not really the subject of this thread - it was just an aside to explain why I increased my oestrogen ie not because I was getting low oestrogen symptoms. In brief at menopause our oestrogen levels drop dramatically (on average) over the next two years especially but T levels continue to decline gradually. Hence the tendency for women sometimes develop more androgenic characteristics (ie hair growth in the "wrong" places, figure more straight up and down ie apple rather than pear shaped due to change in fat distribution etc). Taking oestrogen will counteract this to some extent but taking T might tip the balance. As with much stuff about hormone levels this is not a precise science but as I am taking T did not want to exacerbate this tendency.

Hurdity x

[Hurdity]

Tracey E I get what you're saying about the balance but I think also a sudden increase in oestrogen can cause problems (initially) when a gradual increase may not eg as I said I increased my patch from 50mcg to 62.5 by cutting down a 75 mcg and had no side effects (although others might if very sensitive!). I haven't tried increasing further to 75 mcg only because I want to stay on a longer cycle and don't want heavier bleeds. I'm interested to trynow just to see what happens! After all I waste all those tiny pieces of patch...

Hurdity x

[JayJay]

Hi,

I was on three quarters of a patch of evorel 50 (oestrogen only ) for about 6 months. Due to a sudden dip into depression reminiscent of low mood prior to hrt I went up to a whole patch, with approval of gynae, about 3 weeks ago. The oestrogen has been unopposed with progesterone due to chronic migraine. I am suddenly having more palpitations, (had 24 hr halter a month ago nothing sinister)  abdominal pain/indigestion, bloating, fatigue, nausea, grumpiness (although depression has gone) I wonder if these are now hrt side effects as my dose is too high?

I am having a polyp removed from my endometrium in a couple of weeks and a mirena put in. I am stressed about this so could be that but it seems a bit OTT to be completely attributable to anxiety.

Has anyone had problems with an oestrogen dose too high for them to tolerate? I am thinking of going down to 3 quarters again as the depression, retrospectively, may simply have been news of the impending operation and dealing with uti issues.

Any thoughts welcome.

Hi E
I have just posted on another thread with a problem similar to yours.  Don't know which way to go for the best.
When I feel strong, then all is OK, but just as likely to turn on a sixpence into a jibbering mess.
'abdominal pain/indigestion, bloating, fatigue, nausea, grumpiness'.  Add belly fat to the list, plus crippling lack of confidence.
Hope someone comes along with magic soon  J

[Tracey E]

Hi Sammie, well I've only been on Estradot 75 for 24 hrs, so early doors. Less hot flushes but they still haven't completely gone yet. I had a couple of fluttery heartbeats over the last 24 hrs but bearable. So I'm going to persevere with this dosage for a while longer. My mood is still pfft, weird really because when I was Estrogel I was happy as Larry. I thought the two products were quite similar, just goes to show.

Hurdity I also hate waste of any description and cutting up these patches, well!  For some reason I don't seem to be asorbing these as well as the gel, hence the higher dosage patch. I thought the 24 hr release woukd be kinder to me. Guess you'll never know until you try.

Tracey X

[Sammiejane]

Hi Tracey e

Yes I agree with you there I am finding the estradot patch not as effective in my mood I feel quite irritated on it where as the estrogel I was more calmer and better sleep but my hair has thinned so much although it had started shedding prior to me starting the estrogel and has slowed down so not sure if the estrogel has helped or made it worse as feels thinner but shedding possibly not as much although I am barely brushing it now whilst wet so maybe that has helped but new symtom is excessive sweating in between legs and armpits but wondered can hair vitamins cause this as they promote blood flow to all hair follicles including pubic hair armpit and which can then inturn produce sweating due to rush of blood flow ? I read it on the internet true or not I don't know.

You mentioned you shed hair on estrogel is it still happening in the patch ?

[Tracey E]

It's a bit early to say yet Sammie only started these patches recently, how long have you been in the Estradot 50? I feel a lot more calmer today than yesterday now I've upped my dose from 50 to 75, it takes a few days to kick in..

[JayJay]

Hi Tracey e

Yes I agree with you there I am finding the estradot patch not as effective in my mood I feel quite irritated on it where as the estrogel I was more calmer and better sleep but my hair has thinned so much although it had started shedding prior to me starting the estrogel and has slowed down so not sure if the estrogel has helped or made it worse as feels thinner but shedding possibly not as much although I am barely brushing it now whilst wet so maybe that has helped but new symtom is excessive sweating in between legs and armpits but wondered can hair vitamins cause this as they promote blood flow to all hair follicles including pubic hair armpit and which can then inturn produce sweating due to rush of blood flow ? I read it on the internet true or not I don't know.
Interesting you should say this, as I thought my hair was thinning on oestrogel (and it is very fine to start with).
Anyone else find this side effect with the gel system, as opposed to patches??

You mentioned you shed hair on estrogel is it still happening in the patch ?

[Sammiejane]

Hi Tracey e

I had to up my patch to 75 as on the 50 my sleep was worse but found the increase in hair shedding on 75 and my other concern since being on estrogen in general is the size my boobs have gone up two cup sizes ? Is this normal ?
But I don't know wether to stay on estrogel and try 2.5 pumps and add progesterone 100mg utrogestan every night or stay on estradot patch 50 add progesterone or just take estradot 75 patch. ? I notice u said u don't seem to be obsorbing the patch aswell as the gel so had to up the dose ?

Please tell me what to do I'm at my wits end !

I thinking it would be so easier just to go on contraceptive pill but worry if this would work aswell

[Tracey E]

Hi Tracey e

I had to up my patch to 75 as on the 50 my sleep was worse but found the increase in hair shedding on 75 and my other concern since being on estrogen in general is the size my boobs have gone up two cup sizes ? Is this normal ?
But I don't know wether to stay on estrogel and try 2.5 pumps and add progesterone 100mg utrogestan every night or stay on estradot patch 50 add progesterone or just take estradot 75 patch. ? I notice u said u don't seem to be obsorbing the patch aswell as the gel so had to up the dose ?

Please tell me what to do I'm at my wits end !

I thinking it would be so easier just to go on contraceptive pill but worry if this would work aswell

Initially the size of your breasts will increase but this settles down after a while. How about your other symptons whilst on the patch, sweats etc have they decreased?