Thank you all for answering my queries, I contacted the doctor, she told me to keep as I am for another month, then she will look at changing the oestogen to a patch, I have been on her for about 7years now which started when I was 48, I had the mirena coil and premarin tablets, had that for 5years, I seemed to be ok, had no hot flushes, but was tired a lot,sleep was okish, then had premarin & provera, elleste duet, tibilone, venlafaxine antidepressant 150 which I still take now, femseven patches which seemed to be ok, then discontinued, everol 50, which gave me bleeds and have bled really since then, I had a scan and biopsy which we all fine, had estrogel and utrogestan, that made me so tired I couldn't wake up all day, kliofen,bloated and moody, now sandrena and provera, phew, there's not much else is there but I won't give up, Hense the referral to the Meno clinic, sorry for being long winded xxx