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[Belladonna]

I'm on a month long course of diflucan and haven't been feeling well at all since starting it. Been so bloated and swollen all over, especially lower body. It is not listed as a known side effect of fluconazole, but when I checked for drug interactions I found that diflucan can cause more than a 50% increase in estradiol blood levels as it affects the breakdown of estradiol. I'm already on a pretty high HRT dose because I'm young (my estradiol was over 700 when last tested) so 50% more of that is a lot! And it sure explains why I mysteriously gained 3 kilos in as many days and why my legs feel like they're going to pop open when I bend down.

Has anyone else been on diflucan for weeks or months and how did you feel?  Did you adjust your HRT dosage?

I have decreased my HRT dosage with about 30% now and am hoping that will help. I really wish doctors would check for interactions before prescribing.

[Taz2]

It's so difficult to know what's causing you to feel so horrible but when I was prescribed Diflucan I had those same symptoms but I was not on HRT so I wonder if it could be just the Diflucan? Have you had it before?

Taz x

[CLKD]

Speak to your local pharazmist today, they have private rooms!  Then let us know.