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[racjen]

Could somebody please give me some reassurance - I feel so awful this morning i want to die, this misery has been going on for so long I can't stand it anymore. I know it's worse right now because I've just got through 10 days on 200 mg utrogestan and now I'm in the withdrawal bit, but I feel so anxious, depressed, crying constantly and can't stand it. Somebody please remind me how long this is likely to go on - Monday night was the last dose so it's been a couple of days. I really do want to die,

[Daisydot]

Hi racjen I'm so sorry to hear your feeling yuk.i have no expertise on this but just wanted you to know someone else cares I'm sure one of the wiser ladies will be along to reassure you soon but meantime hang in there you can get through this you just need a wee bit of help and support,take care lots of hugs xx

[Dancinggirl]

Usually things improve one the bleed starts. IT does sound extreme racjen - do you feel OK while actually using the Utrogestan? If so, you may do better with a Mirena which will give you a constant low dose of progesterone that could give you more stable mood?  DG x

[racjen]

No, 10 days of 200mg of utrogestan has already left me feeling extremely depressed, this is just more of the same...don't think I can tolerate that much of it, even if it's only every 3 months.

[Hurdity]

So sorry to hear you are feeling rough after your utrogestan course. My body seems to have adjusted to it so I don't feel too bad although the second morning following the last dose I feel absolutely shattered and can hardly wake up - even more so than when taking it, and as I gear up to my bleed a feel a bit dizzy and spaced out as the stuff leaves my system and as it gets back to normal. I can't remember if you take it orally or vaginally - sorry! It might be placebo but I swear by my method of plumping up the vag tissues by daily Vagifem in the week leading up to my utro course and then keeping it up at least twice a week while taking the utro (vaginally). You might expect more withdrawal side effects if you take it orally because of the metabolic breakdown products of digestion and going through the liver. Hang in there and hope it eases soon when your bleed comes.

Hurdity x

[GypsyRoseLee]

Oh darling, I know how you feel. I have been there so many times. This will pass. It really will. You are obviously very intolerant to progesterone, like a few of us on here. This being the case you really don't want the Mirena coil. I tried it years ago and it had me crawling up the walls within days.

200mg for 12 days is probably just far too much for too long. Now that I only take 100mg for 7 days I don't really notice that I'm taking it. If I get a dip it tends to happen in the week before I start taking Utrogestan.

You really need to explore taking a lower dose for a shorter time, and maybe increase your oestrogen too? Prof Studd told me that some women just need an awful lot of oestrogen to get back to feeling normal again.

Please hold on and keep going. This will pass and all will be well. Just keep talking to us and we'll help you through.

[racjen]

Don't think it's the oestrogen - that's now sky-high (last blood test was over 2000), I seem to absorb that a lot better than many and my dose has been halved. But yes, I think i need to try the shorter regime. Trouble is, it hasn't been suggested by the private specialist i've been seeing (does only Prof. Studd recommend this), and I know my GP will freak out, so do I just go ahead and do it anyway? My inclination is to try it and see what happens, and worry about doctors later...

Hurdity, I take it vaginally, but of course that means that 200mg is an even bigger hit dosewise doesn't it? Does it usually take longer to get a bleed if you've been taking a higher dose like this? Or is that completely random?

[NinaH]

Racjen please don't just go off license - I do understand how you feel (I myself switched to every day 100mcg utrogestan to avoid the fluctuations) however this was done  with the full support and knowledge of my gp.

What's right for some is not right for others. 7 days utrogestan is a very small amount and it might not protect you adequately. Women who do this do so whilst understanding the potential risks associated with such a low dose.   

I hope it works out for you and you find a regime that helps. Good luck x

[racjen]

That doesn't really make sense though - there are loads of women here doing Prof. Studd's recommended 7 days a month 100mg utrogestan and getting on fine with it. Mathematically speaking, 10 days of 200mg every 3 months = 2000mg utrogestan in total. 7 days of 100 mg every month for 3 months = 2100mg. So it's pretty much the same dose. Am I missing something here, is there another factor I'm not taking into account? Otherwise I'm just trying it, doctors really haven't helped me much so far, and I'm not paying Prof Studd several hundred pounds just to be given his standard treatment which I can work out for myself anyway...

[NinaH]

Those women have scans regularly to check their womb lining thickness, which is essential if you are taking an unlicensed dose.

Of course you can do what you want though - it's not something anyone on here would (or should) recommend without specialist guidance.

This is just my opinion though obviously - feel free to ignore it

[CLKD]

Many ladies are intolerant of the progesterone.  It can m are them feel exactly like you describe.   

[racjen]

Yes I know that - I've read plenty of other women's experiences on here. The question is, what do I do about it?

[Dotty]

Have you tried Provera?

[Mary G]

racjen, this is a much debated subject and you might want to read some of my older posts on low dose progesterone.

Like GRL, I'm a patient of Professor Studd and take an even lower dose of progesterone due to severe intolerance.  I do have regular scans with my gynaecologist which confirm that I get good lining clearance and thinning with a fraction of the NHS stated dose.  There is no guarantee that you or anyone else will get the same results as me but the thing to do is find out. 

If you are progesterone intolerant it's pointless to take a high dose and put yourself through hell for years on end if you don't need to. 

If you are progesterone intolerant the best course of action is to try the 7 day 100mg vaginal Utrogestan and then have a scan after a few months which will confirm whether or not it is working.  Most women find it is enough but there will always be some who need more. 

Of course this low dose regime should be available to all women but the NHS don't offer routine uterine scans.  I would argue that it's better health wise to take low dose of progesterone and have benefit of regular scans which will detect other conditions too.

It's about time something better came along.

[GypsyRoseLee]

Hi MaryG 

Prof Studd didn't seem bothered about me even having a scan because my withdrawal bleed, though light, is very regular with no other problem bleeding. He said this was sufficient to prove the Utrogestan was doing its job effectively.