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Menopause Matters magazine ISSUE 81 out now. (Autumn issue, September 2025)

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Author Topic: Pregnenolone  (Read 1995 times)

Chi chi

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Pregnenolone
« on: July 12, 2017, 05:42:40 PM »

Just wondering if Pregnenolone could be used as the prog part of HRT?
I saw a holistic Dr who prescribed Pregnenlone for me to take aswell as lots of other things. I gave up after only a few days as I just felt nothing was going to work with me  :-\
I'm now really down in the dumps and at a complete loss as to what to do for the best?
One half of me is saying try all the things the holistic Dr prescribed again and the other half is saying go back on HRT, I'm just so confused
I'm due on my period tomorrow and we go on holiday in 4 weeks time which means I'll also have my period for the first week which I really don't want  :-\ but will 4 weeks even be enough time to suppress  my cycle if I re start my gels?
I feel so on edge, anxious, snappy, totally miserable and like I'm full of electricity if that even makes any sense  :(
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Hurdity

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Re: Pregnenolone
« Reply #1 on: July 12, 2017, 10:33:22 PM »

Yes as shortie says. You might as well just eat cholesterol as far as I can see. The substance itself is not the rate limiting step but the whole synthesis of steroids in our bodies is under complex enzyme control and multiple feedback loops so you can't just pick something from the steps along the way and hope it will change into what you want it to change into!

Here is the summary diagram of how it all works form Wikipedia:
https://en.wikipedia.org/wiki/Steroid#/media/File:Steroidogenesis.svg

No you cannot use it instead of progesterone! I'm afraid your holistic doctor sounds somewhere further down the snake-oil spectrum than desired !

Not sure why you stopped hRT? Not sure how quickly you can suppress your cycle with just gel though but if you are keen then give it a try-  if you are feeling that bad you won't enjoy your holiday!

Hurdity x
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Chi chi

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Re: Pregnenolone
« Reply #2 on: July 13, 2017, 09:37:44 AM »

Thanks for the replies,
Hurdity the Dr didn't say to use it as the prog part of HRT (sorry should have made that clear)! Just me thinking out aloud as usual  ::)

Am I allowed to name the Dr I saw? I'd be interested to know if anyone else has seen him?
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Chi chi

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Re: Pregnenolone
« Reply #3 on: July 13, 2017, 11:57:53 AM »

Have pm'd you Shortie  ;)
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